Autonomic Pharmacology 2 Flashcards

1
Q

What sort of signals come away from and towards the brain?

A

efferent away from, afferent towards

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2
Q

What are the 3 divisions of the autonomic nervous system?

A

enteric, sympathetic, parasympathetic

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3
Q

What does ANS regulate?

A

functions essential to human health

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4
Q

These functions essential to human health are the voluntary or involuntary?

A

involuntary e.g. whilst asleep

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5
Q

Sympathetic and parasympathetic divisions of the CNS often work how?

A

simultaneously and in a complementary manner

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6
Q

Ach is always the transmitter where?

A

preganglionic, sympathetic and parasympathetic

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7
Q

Preganglionic neurone releases what?

A

ACh

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8
Q

Postganglionic neurone releases what?

A

Noradrenaline

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9
Q

Preganglionic fibres are located where?

A

intermedialateral cell column

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10
Q

Preganglionic cholinergic fibres innervate the adrenal medulla via what?

A

sphlanchnic nerves

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11
Q

Where are the sacral spinal nerves found?

A

S2-S4

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12
Q

Midbrain leads to what ganglion and what post ganglion target?

A

ciliary and eye

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13
Q

Pons leads to what ganglion and what post ganglion target?

A

submandibular and lacrimal gland

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14
Q

Medulla oblongata leads to what ganglion and what post ganglion target?

A

otic and parotid glands

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15
Q

What actually causes depolarisation?

A

Ach binding to ligand gated ion channels and opening them in postganglionic neurone

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16
Q

Are Ach and NA the only two transmitters released form sympathetic and parasympathetic postganglionic fibres?

A

no also NANC

17
Q

Nicotinic ACh receptors of the ganglia are what?

A

ligand gated ion channels

18
Q

Muscarinic ACh receptors of the effector cells are what?

A

G-protein-coupled receptors