Autonomic Pharmacology 1

Question 1

Ca2+ induces what?

Answer 1

release of transmitter

Question 2

Ach receptors consist of what?

Answer 2

five glycoprotein subunits

Question 3

Ganglionic in the peripheral nervous system is made up of what subunits?

Answer 3

alpha 3 and beta 4

Question 4

The CNS has 2 receptors which are made out of what

Answer 4

alpha 7 and the other both alpha 4 and beta 2

Question 5

Name the 3 sites with sympathetic as predominant tone

Answer 5

arterioles, veins and sweat glands

Question 6

All ganglionic transmission is selectively blocked by what?

Answer 6

hexamethonium

Question 7

M1 has what effect when activated?

Answer 7

increased acid secretion

Question 8

M2 has what effect when activated?

Answer 8

decreased heart rate

Question 9

M3 has what effect when activated?

Answer 9

increased secretion

Question 10

Beta 1 activation has what effect?

Answer 10

increased heart rate

Question 11

Beta 2 activation has what effect?

Answer 11

relaxation of bronchial and vascular smooth muscle

Question 12

Alpha 1 activation has what effect?

Answer 12

contraction of vascular smooth muscle

Question 13

Alpha 2 activation has what effect?

Answer 13

inhibition of NA release

Question 14

Do agonists increase or decrease release?

Answer 14

decrease

Question 15

Do antagonists increase or decrease release?

Answer 15

increase

Question 16

Prazosin agonist or antagonist?

Answer 16

antagonist

Question 17

Atenolol agonist or antagonist?

Answer 17

antagonist

Question 18

Salbutamol agonist or antagonist?

Answer 18

agonist