Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

pharmacology final ( 1st sem) > Autonomic NS- Adrenergic > Flashcards

Autonomic NS- Adrenergic Flashcards

1
Q

Direct acting catecholamines

A 
Epinephrine
NE
Dopamine
Isoprenaline
Dobutamine
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Dobutamine Receptor preferance

A

B1 > B2&raquo_space;> a1

doBButAmine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Epinephrine dose dependent effects

A

Low dose- B1, B2 agonist

High dose- a1 agonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Epinephrine indications

A 
Cardiac arrest
Heart block
Anaphylactic shock
Hypotensive crisis
Acute asthma attack
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

NE indications

A

Cardiac arrest
Heart block
Septic, Cardiogenic, Neurogenic shock
Hypotensive crisis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Dopamine dose dependent effects

A

Low dose- D1 stimulation (Increased renal perfusion)
Medium dose- B1 stimulation
High dose- Acts like Epi

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Dopamine indication

A

Shock

With renal failure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Isoprenaline Receptor preferance

A

B1=B2

Iso isl like equally =

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Dobutamine Receptor preferance

A

B1 > B2&raquo_space;> a1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Dobutamine indication

A

Cardiogenic shock
Acute heart failure
Cardiac stimulation in cardiac stress test

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

a- agonists

Receptor preferance

A 
Phenylephrine- a1
Oxymetazoline- local a1, systemic a2
Clonidine- a2, I2
Rimenidine- a2, I2
Methyldopa- a2
Brimonidine- a2
Tizanidine- a2

All -dine suffix is for a2-R
Long words are for a1-R
You cant measure BMR on CT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Clonidine indications

A

Antihypertensive
ADHD
Tourettes
Alcohol withdrawal synd.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Which a-agonist is indicated locally in case of Glaucoma?

Which R?

A

a2-R

Brimonidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Which a-agonist is an orally taken muscle relaxant?

Which R?

A

a2-R

Tizanidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

B2- agonists

A 
Albuterol
Fenoterol
Terbutaline
Salmeterol
Formeterol

AFT and FOR SALE-meterol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Albutarol is also called

A

Salbutamol

17
Q

Short acting B2 agonists

A

Albuterol
Fenoterol
Terbutaline

18
Q

Long acting B2 agonists

A

Salmeterol

Formoterol

19
Q

Besides Asthma treatment, give another indication for Terbutaline?

A

Suppress premature labor

20
Q

Indirect acting sympathomimetics can be 3 types

A

Release inducing
Reuptake inhibitors
MAO inhibitors

21
Q

Indirect acting sympathomimetics

Release inducing

A

Amphetamine
Methylphenidate
Tyramine
Ephedrine

TEAM players!! they help release more

22
Q

Indirect acting sympathomimetics
Reuptake inhibitors
+ MOA

A

Cocaine- NET+DAT inhibition
Atomoxetine- NE reuptake inhibition
Modafinil- NET+DAT inhibition

23
Q

Indirect acting sympathomimetics
MAO inhibitors
+ MOA

A

Tanylcypromine- Non selective, irreversible
Moclobemide- MAO A, reversible
Selegiline- MAO B, reversible

24
Q

Selegiline MOA+ indication

A

MAO B inhibition
Reversible
Parkinson

25
Q

Tanylcypromine, Moclobemide indication

A

Antidepressant

Tanylcypromine is not longer used

26
Q

Direct acting sympatholytics
a antagonists
Which R?

A 
Phentolamine- Non selective
Phenoxybenzamine- Non selective
Prazosin- a1
Doxazosin- a1
Tamsulosin- a1
Urapidil- a1 antag, a2 agon, B antag, 5-HT agon
Mitrazapine- a2
27
Q

Direct acting sympatholytics

Only a1 antagonists

A

Prazosin
Doxazosin
Tamsulosin

28
Q

Direct acting sympatholytics

Non selective a antagonists

A

Phentolamine

Phenoxybenzamine

29
Q

Direct acting sympatholytics

a2 antagonist

A

Mitrazapine

30
Q

Prazosin
Doxazosin
Tamsulosin

Indication

A

HTN

BPH -> relax muscle and allows urination

31
Q

Which a1 antagonist is used in PTSD?

A

Prazosin

אתה צריך לקבל פרס אם אתה עוזר ל
PTSD

32
Q

Non selective B-R antagonists

A

Propranolol
Timolol
Pindolol
Sotalol

Pls Tell People Sorry, we dont treat CHF

33
Q

Selective B-1 antagonists

A 
Bisoprolol
Acebutolol
Nebivolol
Esmolol
Metoprolol

BANE-M
Bane is the 1st bad guy in Batman

34
Q

Combined a and B antag

Which R?

A

Cervedilol
Labetalol

ללללא קקקקריטי להם איזה רצפטור

Both B1, B2, a1 antagonists

35
Q

Which B blockers have the highest lipid solubility?

A

Propranolol
Nebivilol
Bisoprolol

36
Q

Indirect acting sympatholytics

Tyrosine hydroxilase inhibitor

A

Metyrosine

37
Q

Tyrosine hydroxilase- tell me about it

A

Rate limiting step in catecholamine synthesis

Dopamine, NE, Epi..

38
Q

Indirect acting sympatholytics

VMAT inhibitor

A

Reserpine

רסרפין עוצר את הרזרבה

pharmacology final ( 1st sem) (15 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions