Autonomic nervous system questions

Question 1

Neostigmine is effective in relieving abdominal pain in patients with mechanical bowel obstruction

Answer 1

False. Neostigmine is a Reversible Ach E inhibitor and is used to Reverse Neuromuscular blocker effects and in the treatment of myasthenia gravis

Question 2

Neostigmine is used to reverse non-depolarising neuromuscular blockade

Answer 2

True

Question 3

Pilocarpine increases intraocular pressure in patients with open angle glaucoma

Answer 3

False. Pilocarpine is muscarinic agonist that results in the decrease in intraocular pressure in glaucoma.

Question 4

Prolonged use of pilocarpine is associated with tolerance with regular doses

Answer 4

False

Question 5

Atropine causes xerostomia as an adverse effect

Answer 5

True. Adverse effects include: dry mouth (xerostomia), blurred vision, “sandy eyes”, tachycardia , urinary retention, constipation

Question 6

Salbutamol is a beta-2 adrenoceptor antagonist

Answer 6

False. Salbutamol is a beta-2 adrenoceptor agonist

Question 7

Doxazosin decreases total peripheral resistance.

Answer 7

True. Doxazosin is a selective a1 blocker. Therefore, results in VSM dilation.

Question 8

Prolonged use of topical phenylephrine causes rebound congestion of the nasal mucosa

Answer 8

False. Prolonged use of oxymetazoline causes rebound congestion.

Question 9

Phenylephrine is used to reverse hypotension during spinal anaesthesia

Answer 9

True. Indications for phenylephrine include: Nasal decongestant, Hypotension, Mydriatic in eye exams

Question 10

Oxymetazoline is contraindicated in the treatment of acute rhinitis

Answer 10

False.

Question 11

Salbutamol causes a tremor as an adverse effect

Answer 11

True.

Question 12

Propranolol is used in the prophylaxis of migraine headache

Answer 12

True. Propranolol is indicated for: 1. Hypertension 2. Migraine 3. Hyperthyroidism 4. Angina pectoris 5. Myocardial infarction

Question 13

Propranolol has an oral bioavailability of greater than 95%

Answer 13

False.

Question 14

Propranolol is an agonist at beta-1-adrenoceptors

Answer 14

False. Propranolol is a non-selective beta blocker.

Question 15

adrenaline - anaphylactic shock

Answer 15

True

Question 16

atropine - organophosphate poisoning

Answer 16

True

Question 17

dopamine - hypertension

Answer 17

False. Indications : Cardiogenic & septic shock , acute hypotension, severe heart failure

Question 18

Neostigmine - myasthenia gravis

Answer 18

True

Question 19

Phenylephrine - rebound hyperaemia

Answer 19

False. Indications: - Nasal decongestant - Hypotension - Mydriatic in eye exams

Question 20

β1-adrenoceptor agonists cause bradycardia

Answer 20

False. Tachycardia

Question 21

β2-adrenoceptor agonists cause bronchoconstriction

Answer 21

False. Bronchodilation

Question 22

α1-adrenoceptor blockers cause vasodilation

Answer 22

True. VSM vasodilation

Question 23

α2-adrenoceptor agonists cause vasodilation

Answer 23

False. α2 receptors (inhibitory): and inhibits release of NE(NA) *GIT, pancreas, platelets

Question 24

muscarinic receptor stimulation causes tachycardia

Answer 24

False. Bradychardia

Question 25

4. Pharmacological adverse-effects of pseudoephedrine include: a. tremor b. bradycardia c. diarrhoea d. addiction e. hypotension

Answer 25

A. T B. F C. F D. T E. F

Question 26

5. Pharmacological adverse-effects of hyoscine include: a. dry mouth b. bradycardia c. diarrhoea d. abdominal spasms e. urinary retention

Answer 26

Hyoscine is an anticholinergic used as an antispasmodic. A. T B. F C. F D. F E. T

Question 27

What are the functions of Acetylcholine?

Answer 27

1. Decrease in HR and Cardiac output 2. Decrease in blood pressure vd 3. Increased salivation and sweating 4. Increased intestinal secretions, motility and urination 5. Miosis 6. Increased bronchial secretions

Question 28

ANS drug correctly matched with clinical use a. hyoscine - irritable bowel syndrome b. atropine - decongestant c. neostigmine - Myasthenia gravis d. phenylephrine - glaucoma e. salbutamol - asthma

Answer 28

1. T 2. F 3. T 4. F 5. T

Question 29

Pharmacological adverse-effects of neostigmine include a. dry Mouth b. bradycardia c. miosis d. bronchoconstriction e. urinary retention

Answer 29

Neostigmine is ACE inhibitor (prolongs effects of ACH) 1. F 2. T 3. T 4. F 5. F

Question 30

pilocarpine - inhibits muscarinic receptors

Answer 30

False. Muscarinic agonist