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Pharmacology > Autonomic nervous system questions > Flashcards

Autonomic nervous system questions Flashcards

1
Q

Neostigmine is effective in relieving abdominal pain in patients with mechanical bowel obstruction

A

False. Neostigmine is a Reversible Ach E inhibitor and is used to Reverse Neuromuscular blocker effects and in the treatment of myasthenia gravis

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2
Q

Neostigmine is used to reverse non-depolarising neuromuscular blockade

A

True

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3
Q

Pilocarpine increases intraocular pressure in patients with open angle glaucoma

A

False. Pilocarpine is muscarinic agonist that results in the decrease in intraocular pressure in glaucoma.

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4
Q

Prolonged use of pilocarpine is associated with tolerance with regular doses

A

False

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5
Q

Atropine causes xerostomia as an adverse effect

A

True. Adverse effects include: dry mouth (xerostomia), blurred vision, “sandy eyes”, tachycardia , urinary retention, constipation

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6
Q

Salbutamol is a beta-2 adrenoceptor antagonist

A

False. Salbutamol is a beta-2 adrenoceptor agonist

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7
Q

Doxazosin decreases total peripheral resistance.

A

True. Doxazosin is a selective a1 blocker. Therefore, results in VSM dilation.

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8
Q

Prolonged use of topical phenylephrine causes rebound congestion of the nasal mucosa

A

False. Prolonged use of oxymetazoline causes rebound congestion.

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9
Q

Phenylephrine is used to reverse hypotension during spinal anaesthesia

A

True. Indications for phenylephrine include: Nasal decongestant, Hypotension, Mydriatic in eye exams

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10
Q

Oxymetazoline is contraindicated in the treatment of acute rhinitis

A

False.

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11
Q

Salbutamol causes a tremor as an adverse effect

A

True.

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12
Q

Propranolol is used in the prophylaxis of migraine headache

A

True. Propranolol is indicated for: 1. Hypertension 2. Migraine 3. Hyperthyroidism 4. Angina pectoris 5. Myocardial infarction

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13
Q

Propranolol has an oral bioavailability of greater than 95%

A

False.

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14
Q

Propranolol is an agonist at beta-1-adrenoceptors

A

False. Propranolol is a non-selective beta blocker.

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15
Q

adrenaline - anaphylactic shock

A

True

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16
Q

atropine - organophosphate poisoning

A

True

17
Q

dopamine - hypertension

A

False. Indications : Cardiogenic & septic shock , acute hypotension, severe heart failure

18
Q

Neostigmine - myasthenia gravis

A

True

19
Q

Phenylephrine - rebound hyperaemia

A

False. Indications: - Nasal decongestant - Hypotension - Mydriatic in eye exams

20
Q

β1-adrenoceptor agonists cause bradycardia

A

False. Tachycardia

21
Q

β2-adrenoceptor agonists cause bronchoconstriction

A

False. Bronchodilation

22
Q

α1-adrenoceptor blockers cause vasodilation

A

True. VSM vasodilation

23
Q

α2-adrenoceptor agonists cause vasodilation

A

False. α2 receptors (inhibitory): and inhibits release of NE(NA) *GIT, pancreas, platelets

24
Q

muscarinic receptor stimulation causes tachycardia

A

False. Bradychardia

25
Q
  1. Pharmacological adverse-effects of pseudoephedrine include: a. tremor b. bradycardia c. diarrhoea d. addiction e. hypotension
A

A. T B. F C. F D. T E. F

26
Q
  1. Pharmacological adverse-effects of hyoscine include:
    a. dry mouth
    b. bradycardia
    c. diarrhoea
    d. abdominal spasms
    e. urinary retention
A

Hyoscine is an anticholinergic used as an antispasmodic.

A. T

B. F

C. F

D. F

E. T

27
Q

What are the functions of Acetylcholine?

A
  1. Decrease in HR and Cardiac output
  2. Decrease in blood pressure vd
  3. Increased salivation and sweating
  4. Increased intestinal secretions, motility and urination
  5. Miosis
  6. Increased bronchial secretions
28
Q

ANS drug correctly matched with clinical use

a. hyoscine - irritable bowel syndrome
b. atropine - decongestant
c. neostigmine - Myasthenia gravis
d. phenylephrine - glaucoma
e. salbutamol - asthma

A
  1. T
  2. F
  3. T
  4. F
  5. T
29
Q

Pharmacological adverse-effects of neostigmine include

a. dry Mouth
b. bradycardia
c. miosis
d. bronchoconstriction
e. urinary retention

A

Neostigmine is ACE inhibitor (prolongs effects of ACH)

  1. F
  2. T
  3. T
  4. F
  5. F
30
Q

pilocarpine - inhibits muscarinic receptors

A

False. Muscarinic agonist

Pharmacology (13 decks)

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