Autonomic nervous system pharmacology

Question 1

P450 inducers

Answer 1

“Barb uses Phen-phen, Cigarettes, and Ethanol but Refuses Greasy Carbs”

• Barbiturates
• Phenytoin
• Cigarette smoke
• Ethanol (alcohol)
• Rifampin
• Griseofulvin (for fungus infection)
• Carbamazepine (seizure drug, especially partial seizures)

Question 2

P450 inhibitors

Answer 2

“Inhibitors Stop Cyber-Kids from Eating Ripe Grapefruit And Flying Very Quickly to Distant Metropolis City”

• Isoniazid (for TB)
• Sulfonamides
• Cimetidine (duodenal and gastric ulcers, acid reflux)
• Ketoconazole (dermatitis)
• Erythromycin
• Ritonavir (HIV drug)
• Grapefruit juice
• Amiodarone (arrhythmias)
• Fluoxetine (SSRI)
• Verapamil (blood pressure, arrhythmia, angina)
• Quinidine (irregular heartbeat also maybe malaria)
• Disulfiram (alcoholism)
• Metronidazole (bacterial infections)
• Ciprofloxacin

Question 3

Dobutamine

Answer 3

• used for heart failure and cardiogenic shock

- Beta-1 receptor agonist