Autonomic Nervous System drugs Flashcards
It is the part of the nervous system that controls muscles of internal organs (such as the heart, blood vessels, lungs, stomach, and intestines) and glands (such as salivary glands and sweat glands).
Autonomic Nervous System
-INVOLUNTARY control
What is the difference between Afferent and Efferent?
Afferent- It carries sensory information from receptors in skin or other organs through CNS
- It detects changes inside and outside of the body.
Example: touching a hot pan, the sensory afferent neurons send information about that stimulus up the spinal cord to the brain where association neurons will decide how to respond.
Efferent- This is where Nervous System send out the response based on the analyzed stimulus.
Example: such as removing your hand from a hot pan, they are the neurons that tell your body to perform an action
What is Somatic Nervous System?
This a composition of different nerves in the body that provides VOLUNTARY control of skeletal muscles.
It is the UK term for Epinephrine
Adrenaline
Fibers that run from the ganglion to the effector organ
POSTGANGLIONIC FIBER
This activates the fight or flight response during a threat or perceived danger
Sympathetic Nervous System
-ADRENERGIC
It inhibits the body from overworking and restores the body to a calm and composed state. Rest-and-digest or freed and breed activities
Parasympathetic Nervous System
-CHOLINERGIC
What are the 5 steps for Synaptic transmission?
Step 1: Synthesis of the neurotransmitter
Step 2: Storage
Step 3: Release of the neurotransmitter
Step 4: Action of the receptor
Step 5: Termination of the transmission
Key that fits the Lock
Agonist
-Drugs that produces a response
Key that doesn’t fit the Lock
Antagonist
-Because it blocks the response to the target cells (natural chemical will not fit)
-Effects are determined by the inhibitory action of the drug
When Autonomic disorder are given, the goal is not to treat an Autonomic disorders of target organs through Autonomic Nerves
Pharmacologic effect
Adrenergic agonists and Adrenergic blockers
Alpha-1 receptor: Smooth muscle contraction, mydriasis
Alpha-2 receptor: Mixed smooth muscle effects
Beta-1 receptor: Increased cardiac chronotropic and inotropic effects
Beta-2 receptor: Bronchodilation
This has a catechol ring and amines
Catecholamines
This has no catechol ring
Non-Catecholamines
It influences one type of receptor
Selective
