Antibiotic Drugs Flashcards
What are the 5 mechanisms of Antibacterial action?
- inhibition of bacterial cell-wall synthesis
- alteration of membrane permeability
- inhibition of protein synthesis
- inhibition of the synthesis of bacterial RNA and DNA
- interference with metabolism within the cell
What happen when bacteria is resistant to the drug?
The pathogen will continue to grow despite administration
Addictive effect
Equal to the sum of the effects of two antibiotics
Potentiative effect
Occurs when one antibiotic increases the effectiveness of the 2nd drug
Antagonistic effect
When two drugs are used together, the desired effect may be greatly reduced
Empiric therapy
When a drug selected is known to be the best drug that can kill the MO
Subtherapeutic
When signs and symptoms do not improve
It is characterized by granulomas in the lungs from accumulation of inflammatory cells with a cheesy caseated consistency
Tuberculosis
What is the meaning of the acronym RIPES?
R- rifampicin
I- isoniazid
P- pyrazinamide
E- ethambutol
S- streptomycin
What is the meaning of the acronym RIPES?
R- rifampicin
I- isoniazid
P- pyrazinamide
E- ethambutol
S- streptomycin
It is the term used to describe fungal infection
Myocis
It binds and alters parasitic DNA
Primaquine
What are anti-helminthic drugs?
They are very specific with the worms they can kill, thus accurate identification of causative organisms prior to treatment is necessary
Increases permeability of the cell membrane of the worm which causes dislodgement on the site of residence which they are then killed by the host
Praziquantel
It blocks ACh which results to paralysis of the worm
Pyrantel
