Autonomic nervous system Flashcards
What is the sensory input of the ANS?
- mostly interoreceptors
- some somatic senses
- some special senses
• GVA, SVA, Cranial/spinal nerves
What is the control of motor output of the ANS?
- involuntary from hypothalamus limbic system, brain stem, spinal cord
- limited from cerebral cortex
What is the LMN pathway of the ANS?
2-neuron pathway:
• preganglionic neuron (from CNS)
-> postganglionic neuron (autonomic ganglion)
-> visceral effector
What are the neurotransmitters and hormones of the ANS?
- ACh -acetylcholine
- NE- norepinephrine
- epinephrine
What are the effectors of the ANS?
- smooth muscle
- cardiac muscle
- glands
What are the types of responses from the ANS?
- contraction/relaxation of smooth muscle
- increased/decreased rate and force of contraction of cardiac muscle
- increase/decrease gland secretion
Describe the myelination of neurons along the ANS?
- preganglionic neurons are myelinated
* postganglionic neurons are not
List the receptors of the ANS?
- Nicotinic
- Muscurinic
- Visceral (baro, stretch, chemo, osmotic & glucose, visceral pain, thermal)
Compare nicotinic vs muscurinic receptors
Nicotinic
• ligand-gated ion channels
• faster acting
• sensitive to nicotine
Muscurinic
• G-protein coupled receptor that uses G-protein and secondary messenger system to open ion channel
• sensitive to muscurine (amanita muscaria)
Baroreceptor
- in carotid sinus and large arteries -signal change in pressure
- in atria -signal change in blood volume
Stretch receptors
- lung inflation / deflation
* signal distension in hollow organs (bladder, gut)
Chemoreceptors
- O2 receptors in carotid body and aortic arch
* central chemo signal pH and PCO2
Are sensory afferents of the ANS all subconscious?
- mostly yes
* some are conscious: nausea, hunger, pain
What is the path of the sensory afferents of the ANS?
- run within spinal nerves/ splanchnic nerves that carry ANS efferents
- in the spinal cord, run with somatosensory ascending tracts and anterolateral tracts
Where does afferent sensory ANS information go?
- thalamus
- reticular formation
- hypotalamus
- insular cortex
- solitary nucleus of brainstem
- limbic system
- sensory cortex