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Pharmacology > Autonomic Nervous System > Flashcards

Autonomic Nervous System Flashcards

1
Q

Alpha 1 receptor agonists and usage (2)

A

Phenyphidrine
Oxymetazoline (ophthalmology)

Nasal decongestants

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2
Q

Alpha 1 receptor antagonists and usage (5)

A 
Prazosin - HT
Doxazosin
Terazosin
Tamulosin - prostatic hypertrophy
Resperine
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3
Q

Alpha 2 receptor

A

Auto-inhibition

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4
Q

Meaning of auto-inhibition

A

When the substance binds to the receptor it is taken up, thus the effect will decrease.

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5
Q

Alpha 2 receptor agonists and usage

A

Clonidine - reduce BP

Methyldopa - BP in pregnancy

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6
Q

Alpha 2 receptor antagonists (3)

A

Mianserin
Phentolamine
Phenoxybenzamine

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7
Q

Beta 1 receptor agonists and usage

A

Dobutamine - cardiogenic shock

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8
Q

Beta 1 receptor antagonists

A

Atenolol

Propanolol - acute sinus bradycardia

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9
Q

Beta 2 receptor agonists and usage

A

Salbutamol
Terbutaline
Salmeterol

Bronchodilators
Stop labour

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10
Q

Beta 2 receptor antagonists

A

Propanolol

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11
Q

Reuptake inhibitors

A

Cocaine

TCA

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12
Q

Reuptake inhibitors side effects

A

CNS - euphoria, excitement
Tachycardia
Cardiac arrhythmias

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13
Q

Drugs interfering with catecholamine synthesis

A

Methyldopa
Alpha-methyltyrosine - phaeochromocytoma
Carbidopa
6-hydroxydopamine and MPTP - neurotoxins: destroy nerves after its taken up

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14
Q

Reserpine

A

Block NA take up into vesicles

Used as anti-hypertensive

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15
Q

Nicotinic receptor agonists

A

Nicotine

Lobeline

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16
Q

Nicotinic receptor antagonist

A

Hexamethonium

Trimetaphan

17
Q

M2 - receptor agonists

A

Pilocarpine - glaucoma

18
Q

M2 - receptor antagonists

A

Atropine

19
Q

M3 receptor agonists

A

Pilocarpine

Bethanechol - bladder emptying and GIT motility increase

20
Q

Enzyme inactivators

A

Donepezil
Physostigmine
Neostigmine
Pyridostigmine

21
Q

Parasympatholytics

A 
Atropine - antispasmodic, organophosphate poisoning
Scopolamine - motion sickness
Ipratopium - bronchodilator
Cyclopentolate - myadrisis
Tropicandine - eye drops
Pirenzipine - PUD
Oxybutinin - urinary incontinence

Pharmacology (4 decks)

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