Autoinflammatory & Autoimmune Disease 2 Flashcards

1
Q

What antibody is associated with this organ-specific autoimmune disease? - Goodpasture disease

A. Anti-GAD antibody
B. Anti-thyroglobulin antibody
C. Anti-basement membrane antibody
D. Anti-intrinsic factor antibody
E. Anti-acetylcholine receptor antibody
F. Anti-TSH receptor antibody
A

C. Anti-basement membrane antibody

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2
Q

What antibody is associated with this organ-specific autoimmune disease? - Myasthenia gravis

A. Anti-GAD antibody
B. Anti-thyroglobulin antibody
C. Anti-basement membrane antibody
D. Anti-intrinsic factor antibody
E. Anti-acetylcholine receptor antibody
F. Anti-TSH receptor antibody
A

E. Anti-acetylcholine receptor antibody

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3
Q

What antibody is associated with this organ-specific autoimmune disease? - Graves disease

A. Anti-GAD antibody
B. Anti-thyroglobulin antibody
C. Anti-basement membrane antibody
D. Anti-intrinsic factor antibody
E. Anti-acetylcholine receptor antibody
F. Anti-TSH receptor antibody
A

F. Anti-TSH receptor antibody

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4
Q

What antibody is associated with this organ-specific autoimmune disease? - Pernicious anaemia

A. Anti-GAD antibody
B. Anti-thyroglobulin antibody
C. Anti-basement membrane antibody
D. Anti-intrinsic factor antibody
E. Anti-acetylcholine receptor antibody
F. Anti-TSH receptor antibody
A

D. Anti-intrinsic factor antibody

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5
Q

What antibody is associated with this organ-specific autoimmune disease? - Diabetes mellitus

A. Anti-GAD antibody
B. Anti-thyroglobulin antibody
C. Anti-basement membrane antibody
D. Anti-intrinsic factor antibody
E. Anti-acetylcholine receptor antibody
F. Anti-TSH receptor antibody
A

A. Anti-GAD antibody

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6
Q

What antibody is associated with this organ-specific autoimmune disease? - Hashimoto thyroiditis

A. Anti-GAD antibody
B. Anti-thyroglobulin antibody
C. Anti-basement membrane antibody
D. Anti-intrinsic factor antibody
E. Anti-acetylcholine receptor antibody
F. Anti-TSH receptor antibody
A

B. Anti-thyroglobulin antibody

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7
Q

May be positive in a patient with idiopathic inflammatory myopathy with interstitial lung disease

A. Anti-Ro antibody
B. Anti-Jo1 (tRNA synthetase) antibody
C. Anti-SCL70 antibody
D. Anti-dsDNA antibody
E. Anti-centromere antibody
A

B. Anti-Jo1 (tRNA synthetase) antibody

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8
Q

May be positive in SLE or Sjogren’s syndrome

A. Anti-Ro antibody
B. Anti-Jo1 (tRNA synthetase) antibody
C. Anti-SCL70 antibody
D. Anti-dsDNA antibody
E. Anti-centromere antibody
A

A. Anti-Ro antibody

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9
Q

Specific for limited cutaneous systemic sclerosis

A. Anti-Ro antibody
B. Anti-Jo1 (tRNA synthetase) antibody
C. Anti-SCL70 antibody
D. Anti-dsDNA antibody
E. Anti-centromere antibody
A

E. Anti-centromere antibody

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10
Q

Most specific antibody for SLE

A. Anti-Ro antibody
B. Anti-Jo1 (tRNA synthetase) antibody
C. Anti-SCL70 antibody
D. Anti-dsDNA antibody
E. Anti-centromere antibody
A

D. Anti-dsDNA antibody

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11
Q

Specific for diffuse cutaneous scleroderma

A. Anti-Ro antibody
B. Anti-Jo1 (tRNA synthetase) antibody
C. Anti-SCL70 antibody
D. Anti-dsDNA antibody
E. Anti-centromere antibody
A

C. Anti-SCL70 antibody

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12
Q

Vasculitis: ANA (Anti-nuclear antibody)

A. Screening test for a connective tissue disease
B. Associated with a subset of small vessel vasculitides including MPA, GPA and eGPA

A

A. Screening test for a connective tissue disease

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13
Q

Vasculitis: ANCA (Anti-neutrophil cytoplasmic antibody)

A. Screening test for a connective tissue disease
B. Associated with a subset of small vessel vasculitides including MPA, GPA and eGPA

A

B. Associated with a subset of small vessel vasculitides including MPA, GPA and eGPA

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