Autoinflammatory & Autoimmune Disease 1 Flashcards

1
Q

Type III hypersensitvity

  1. Goodpasture disease
  2. Eczema
  3. SLE
  4. Multiple sclerosis
A
  1. SLE
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2
Q

Type I hypersensitvity

  1. Goodpasture disease
  2. Eczema
  3. SLE
  4. Multiple sclerosis
A
  1. Eczema
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3
Q

Type IV hypersensitvity

  1. Goodpasture disease
  2. Eczema
  3. SLE
  4. Multiple sclerosis
A
  1. Multiple sclerosis
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4
Q

Type II hypersensitvity

  1. Goodpasture disease
  2. Eczema
  3. SLE
  4. Multiple sclerosis
A
  1. Goodpasture disease
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5
Q

IPEX (Immune dysregulation, polyendocrinopathy, enteropathy, X linked)

A. Single gene mutation involving MEFV and affecting the inflammasome complex, resulting in recurrent episodes of serositis
B. Mutations within the Fas pathway associated with lymphocytosis, lymphomas and auto-immune cytopenias
C. Single gene mutation involving FOXp3 resulting in abnormality of T-reg cells

A

C. Single gene mutation involving FOXp3 resulting in abnormality of T-reg cells

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6
Q

Familial Mediterranean Fever

A. Single gene mutation involving MEFV and affecting the inflammasome complex, resulting in recurrent episodes of serositis
B. Mutations within the Fas pathway associated with lymphocytosis, lymphomas and auto-immune cytopenias
C. Single gene mutation involving FOXp3 resulting in abnormality of T-reg cells

A

A. Single gene mutation involving MEFV and affecting the inflammasome complex, resulting in recurrent episodes of serositis

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7
Q

Auto-immune lymphoproliferative syndrome (ALPS)

A. Single gene mutation involving MEFV and affecting the inflammasome complex, resulting in recurrent episodes of serositis
B. Mutations within the Fas pathway associated with lymphocytosis, lymphomas and auto-immune cytopenias
C. Single gene mutation involving FOXp3 resulting in abnormality of T-reg cells

A

B. Mutations within the Fas pathway associated with lymphocytosis, lymphomas and auto-immune cytopenias

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