Autoimmune Hepatitis Flashcards
1
Q
How is diagnosis of autoimmune hepatitis determined?
A
Exclusion: rule out viruses, drugs, metabolic or genetic causes
2
Q
What are the extra hepatic manifestations of autoimmune hepatitis?
A
- sicca
- Raynaud’s
- thyroiditis
- Sjogren’s
- arthralgias
- hypergammaglobulinemia (anti Smooth muscle Ab most common); ANA, RF
3
Q
Biopsy signs of ai hepatitis?
A
-Periportal (zone 1) and interface inflammation and necrosis
4
Q
Mx ai chronic active hepatitis?
A
- Corticosteroids
- Azathioprine