Autoimmune Hepatitis Flashcards

1
Q

How is diagnosis of autoimmune hepatitis determined?

A

Exclusion: rule out viruses, drugs, metabolic or genetic causes

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2
Q

What are the extra hepatic manifestations of autoimmune hepatitis?

A
  • sicca
  • Raynaud’s
  • thyroiditis
  • Sjogren’s
  • arthralgias
  • hypergammaglobulinemia (anti Smooth muscle Ab most common); ANA, RF
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3
Q

Biopsy signs of ai hepatitis?

A

-Periportal (zone 1) and interface inflammation and necrosis

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4
Q

Mx ai chronic active hepatitis?

A
  • Corticosteroids

- Azathioprine

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