Autogenous Blood Maxilo Flashcards

1
Q

Aim of Regenerative surgical intervention?

Key & note
Regenerative khodesh ye vazheye khase
Yade
Pro
Prf
Minima surgary bioft

A

Restore defects with original tissue
with the help of minimal surgical intention

(Nokte mogem : - minimal surgary
-original tissue )

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2
Q

Aim of Reconstructive sugary Restore defect
with….

A

other tissue

Note: ghabli original bod in other tissue

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3
Q

stage of wound healing? Name: with key)

A

I. P. R
Inflamatory
proliferative
Regenerative

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4
Q

Tell us some info about informatory phase

A
  • 24-48 h after injury
  • blood coagulation (لخته)plat lets. cytokines. growth factor
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5
Q

proliferative phase info?

A
  • 3 days after injury
  • Fibroblasts
  • angiogenesis (production el vessels.)

Key:
Pro 3 harf dare 3 ta ham mired dare

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6
Q

Regenerative phase info?

A
  • Newly organized collagen Fibrils.
  • tissue regeneration

Key va tamrin:
Collagen fibril
Collagen fibril
Fibril zhiglir
100 times begoooooo

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7
Q

Application of full blood?

A
  • plasma
  • RBC
  • planet
    Achilles.
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8
Q

Application of plasma? & Forms?

A

Forms-_fresh _Frozen
- isolated coagulation factor deficiency
- Fibrin glue

Kilid lazem:

Fekon man plasmam
Yakh bezane dare ab mishe mesle chasbe

Chatgpt:
Definition of fibiitin.
Pas fibrin k kheili moheme az plasma

Fibrin is a fibrous protein involved in the clotting of blood. It forms a mesh-like structure, helping to stop bleeding by creating a blood clot at the site of injury.

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9
Q

Fibrin give application?

A

cardiac, vascular, thoracic, nerve, eye, head and neck,

plastic, 👈🏻restorative, accident surgery👈🏻tissue grafting👈🏻liver, spleen parenchyma injury, cannulation,

vascular anastomosis 👈🏻

CHATGPT

Fibrin is a fibrous protein involved in the clotting of blood. It forms a mesh-like structure, helping to stop bleeding by creating a blood clot at the site of injury.

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10
Q

Application of RBC concentrates: & Forms?

A

Forms:
- Frozen
- Filtered
- washed
App: Chronica/ Anemia

Kew
F
W
F

الماني بگو
ف و ف

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11
Q

ADV of platlet products?

A
  • Autogenous tissues(goldstandard)
    -Speeding the revascularisation oftissues(angiogenesis)
  • Recruiting (جذب)various cells including stem cells
  • Speeding the proliferation

Key:

Platlet P dare pas speed Pproliferatiob

Hala k speen ro gofti pas speeding revascularization (angiogenesis

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12
Q

Platlet before. After?
مهم 🔥

A

20 years ago: platlet & growth factor (PDGF) key regulation during
wound healing
Nowdgs :(Aim to concentrates these cells using Anti coaguagvlants
& centrifuge n device.

چرا به كمك اين سلولها ؟ چون اينا جاوتر براي ساخت prp prf هستند

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13
Q

Component takes part in wound healing?

A

-blood plasma
- RBS
-WBC
- planets

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14
Q

Role of plat lets?

A

• Key role in wound healing
•growth factor ( ino CHATGPT ham gofte ,angiogenicfactors,releasing cytokines
• low density

SUMMARY:
GF is kocated at blood plasma
Then PALATLET produce carois growth factor

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15
Q

Role of WBC?

A

• Host defence,regenerative phase of healing ,leukocytes
•Highdensity,sametotheRCBs,hardtoseparate

Note:
جنده سفيد
ReGENerative key cell is : WHITE blood cell

Key:
So
Platlet low density
Wbc high density

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16
Q

Component in Regenerative phase is…..?

A
  • WBC (Leukocyte)

Key
Reجندهrative : jendehaye sefid (white)

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17
Q

PRP is?

A

planets-Rich plasma

Key and chatgpt
Palatelet is secret growthfactor

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18
Q

How to active high conc plat lets?

A

High accumulation of platelets ang growth factors after centrifugation

• Production:30-60 minutes centrifugation,use of anticoagulants altogether

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19
Q

Dis. ADV of PRP?

A
  • Long production time
  • use of anticoagulant (to stop blood clotting before
    Application)
  • Liquid consistence
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20
Q

what is PRF?

A

plat let-Rich fibrin

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21
Q

PRF compare to prp?

A
  • Less centrifuge time
  • without anticoagulants
  • Three layer (PPP-PRF- red corpuscles base)
  • longer growth factor release profile
  • Leukocyte between Fibrin clot & Red corporals
    layer
  • it is not only accumulation of cells & growth factor
    but also a scaffold
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22
Q

Forms of PRF?

A

PRF membrane
PRF plug
sticky bone
inflitrative i-PRF (liquid)
E- PRF membrane

23
Q

3 layer of PRF is ppp, PRF %.?

A

Red Corpus cels base

24
Q

ppp?

A

as cellular plasma

25
PRF?
Fibrin clot
26
main component of PRF.
Bioactive molecules: PDGF,TGF-B , IGF, EGF provisonal extracellular matrix (3D scaffold): fibrin Matrix: Fibronectin , Vitronectin cell types: planets> Leukocytes GRBC
27
How to make PRF?
- Fixed angle centrifugation technique (4s deg) - Horizontal centrifugation technique.
28
protocols for PRF: L-PRF & A- PRF?
L-PRF = (Leukocyte-PRF): 2500_3000 rpm 10-12min A- PRF = (Advanced - PR F) : 1300 rpm 8 minutes
29
Advantage of A- PRF ?
better distribution of planets Leukocyte in the Fibrin alot
30
protocol for I_PRF 7
injectable-PRF 500 RPM 3min liquid consistence longer 655 release profile
31
protocol H-PRF?
- horizontal prf - 700 RPM - 8min - horizontal centrifugation Technique - 4 times greater Leuk & platlet A cumulation in Fibrin clot
32
• .. has 4 times bigger accumulation of Leokcfplatlet in fibvi clot
H-PRF
33
protocol of C- PRF?
• concentrated-PRF - 2000g - 8min - Horizontal cent Technique - highest accumulation of Leukilplatlet (10 -7s time) in fibrin clot
34
mention 2 horizontal centrifugation technique PRF?
- H-PRF • C- PRF
35
Application of PRF in head & neck Region?
1- Oral surgery 2- Regenerative endodontics 3- implant ology 4- Parond otology
36
Application of PRF in oral surgery?
extactionsitemanagement,cystostomy,toothluxation,sinusapertus, MRONJ, osteoradionecrosis,TMI disorders, cleft alveolar bone defects
37
Application of PRF in Regeratire endodontics?
directpulpcapping,pulpotomy,apexification,endodontic
38
Application al PRF in implant ◦ logy?
alveolarperservattion,GBR,sinus-lift,periimplatitis
39
Application al PRF in par ontology?
gingivalrecession,furcationdefects,regenerativeparodontological treatments
40
After extraction impacted 3rd molar & complicated healing? How PRF helps us?
41
PRF in MRONJ:
medication -related osteonecrosis of jaw can happen spontaneous or after intervention.
42
PRF in MRONJ: 2
With the application more than 80% succesrate could be reach Effects: formation of a fibrin network, adhesion of leukocytes and platelets, slow growth factor release, thereby increasing the regeneration tendency of soft and hard tissues
43
PRF in cystectomy; after Removal cyst wall, we should do?
fill bone cavity with PRF
44
what if we fill bone cavity by PRF after cystectomy
y - Formation fibrin mesh (then) stabilize blood clot (then) helps bone regeneration.
45
PRF in cystotomy (tos)
improve QOL faster Regeneration
46
PRF in Endodontics involve:
- Apexifi cation - Direct pulp capping
47
Direct pulp raping vs PRF?
PRF enhance: immun Response increase dentin oogenesis mineralization by slow release al growth factor
48
Best result of Direct pulp capping is use of PRF and ... together.
Mta
49
MTA in Direct pulp capping increase...?
odontoblast differentiation
50
pulp capping success depends on?
technique material tissue reaction
51
Apexifi cation definition?
closing Apical foramen with medication. usually calcium. hydroxide stakes 6 month.
52
How result angiogenesis? (in Apexifi cation)
MTA + PRF + VEGF
53
Apexification: medication like (?) after 6 month and several visit we see (?)
calcium-hydroxide Apical barrier
54
Apexification medication like MTA after How many visit we can see Apical plug
(2 visit) (Apical plug) (not barrier)