Autogenous Blood Maxilo Flashcards

1
Q

Aim of Regenerative surgical intervention?

Key & note
Regenerative khodesh ye vazheye khase
Yade
Pro
Prf
Minima surgary bioft

A

Restore defects with original tissue
with the help of minimal surgical intention

(Nokte mogem : - minimal surgary
-original tissue )

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2
Q

Aim of Reconstructive sugary Restore defect
with….

A

other tissue

Note: ghabli original bod in other tissue

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3
Q

stage of wound healing? Name: with key)

A

I. P. R
Inflamatory
proliferative
Regenerative

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4
Q

Tell us some info about informatory phase

A
  • 24-48 h after injury
  • blood coagulation (لخته)plat lets. cytokines. growth factor
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5
Q

proliferative phase info?

A
  • 3 days after injury
  • Fibroblasts
  • angiogenesis (production el vessels.)

Key:
Pro 3 harf dare 3 ta ham mired dare

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6
Q

Regenerative phase info?

A
  • Newly organized collagen Fibrils.
  • tissue regeneration

Key va tamrin:
Collagen fibril
Collagen fibril
Fibril zhiglir
100 times begoooooo

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7
Q

Application of full blood?

A
  • plasma
  • RBC
  • planet
    Achilles.
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8
Q

Application of plasma? & Forms?

A

Forms-_fresh _Frozen
- isolated coagulation factor deficiency
- Fibrin glue

Kilid lazem:

Fekon man plasmam
Yakh bezane dare ab mishe mesle chasbe

Chatgpt:
Definition of fibiitin.
Pas fibrin k kheili moheme az plasma

Fibrin is a fibrous protein involved in the clotting of blood. It forms a mesh-like structure, helping to stop bleeding by creating a blood clot at the site of injury.

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9
Q

Fibrin give application?

A

cardiac, vascular, thoracic, nerve, eye, head and neck,

plastic, 👈🏻restorative, accident surgery👈🏻tissue grafting👈🏻liver, spleen parenchyma injury, cannulation,

vascular anastomosis 👈🏻

CHATGPT

Fibrin is a fibrous protein involved in the clotting of blood. It forms a mesh-like structure, helping to stop bleeding by creating a blood clot at the site of injury.

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10
Q

Application of RBC concentrates: & Forms?

A

Forms:
- Frozen
- Filtered
- washed
App: Chronica/ Anemia

Kew
F
W
F

الماني بگو
ف و ف

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11
Q

ADV of platlet products?

A
  • Autogenous tissues(goldstandard)
    -Speeding the revascularisation oftissues(angiogenesis)
  • Recruiting (جذب)various cells including stem cells
  • Speeding the proliferation

Key:

Platlet P dare pas speed Pproliferatiob

Hala k speen ro gofti pas speeding revascularization (angiogenesis

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12
Q

Platlet before. After?
مهم 🔥

A

20 years ago: platlet & growth factor (PDGF) key regulation during
wound healing
Nowdgs :(Aim to concentrates these cells using Anti coaguagvlants
& centrifuge n device.

چرا به كمك اين سلولها ؟ چون اينا جاوتر براي ساخت prp prf هستند

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13
Q

Component takes part in wound healing?

A

-blood plasma
- RBS
-WBC
- planets

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14
Q

Role of plat lets?

A

• Key role in wound healing
•growth factor ( ino CHATGPT ham gofte ,angiogenicfactors,releasing cytokines
• low density

SUMMARY:
GF is kocated at blood plasma
Then PALATLET produce carois growth factor

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15
Q

Role of WBC?

A

• Host defence,regenerative phase of healing ,leukocytes
•Highdensity,sametotheRCBs,hardtoseparate

Note:
جنده سفيد
ReGENerative key cell is : WHITE blood cell

Key:
So
Platlet low density
Wbc high density

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16
Q

Component in Regenerative phase is…..?

A
  • WBC (Leukocyte)

Key
Reجندهrative : jendehaye sefid (white)

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17
Q

PRP is?

A

planets-Rich plasma

Key and chatgpt
Palatelet is secret growthfactor

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18
Q

How to active high conc plat lets?

A

High accumulation of platelets ang growth factors after centrifugation

• Production:30-60 minutes centrifugation,use of anticoagulants altogether

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19
Q

Dis. ADV of PRP?

A
  • Long production time
  • use of anticoagulant (to stop blood clotting before
    Application)
  • Liquid consistence
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20
Q

what is PRF?

A

plat let-Rich fibrin

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21
Q

PRF compare to prp?

A
  • Less centrifuge time
  • without anticoagulants
  • Three layer (PPP-PRF- red corpuscles base)
  • longer growth factor release profile
  • Leukocyte between Fibrin clot & Red corporals
    layer
  • it is not only accumulation of cells & growth factor
    but also a scaffold
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22
Q

Forms of PRF?

A

PRF membrane
PRF plug
sticky bone
inflitrative i-PRF (liquid)
E- PRF membrane

23
Q

3 layer of PRF is ppp, PRF %.?

A

Red Corpus cels base

24
Q

ppp?

A

as cellular plasma

25
Q

PRF?

A

Fibrin clot

26
Q

main component of PRF.

A

Bioactive molecules: PDGF,TGF-B , IGF, EGF
provisonal extracellular matrix (3D scaffold): fibrin Matrix:
Fibronectin , Vitronectin
cell types: planets> Leukocytes GRBC

27
Q

How to make PRF?

A
  • Fixed angle centrifugation technique (4s deg)
  • Horizontal centrifugation technique.
28
Q

protocols for PRF:
L-PRF & A- PRF?

A

L-PRF = (Leukocyte-PRF):
2500_3000 rpm
10-12min

A- PRF = (Advanced - PR F) :
1300 rpm
8 minutes

29
Q

Advantage of A- PRF ?

A

better distribution of planets Leukocyte in the Fibrin alot

30
Q

protocol for I_PRF 7

A

injectable-PRF
500 RPM
3min
liquid consistence
longer 655 release profile

31
Q

protocol H-PRF?

A
  • horizontal prf
  • 700 RPM
  • 8min
  • horizontal centrifugation Technique
  • 4 times greater Leuk & platlet A cumulation in Fibrin clot
32
Q

• .. has 4 times bigger accumulation of Leokcfplatlet
in fibvi clot

A

H-PRF

33
Q

protocol of C- PRF?

A

• concentrated-PRF
- 2000g
- 8min
- Horizontal cent Technique
- highest accumulation of Leukilplatlet (10 -7s time)
in fibrin clot

34
Q

mention 2 horizontal centrifugation technique
PRF?

A
  • H-PRF
    • C- PRF
35
Q

Application of PRF in head & neck
Region?

A

1- Oral surgery
2- Regenerative endodontics
3- implant ology
4- Parond otology

36
Q

Application of PRF in oral surgery?

A

extactionsitemanagement,cystostomy,toothluxation,sinusapertus, MRONJ, osteoradionecrosis,TMI disorders, cleft alveolar bone defects

37
Q

Application of PRF in Regeratire endodontics?

A

directpulpcapping,pulpotomy,apexification,endodontic

38
Q

Application al PRF in implant ◦ logy?

A

alveolarperservattion,GBR,sinus-lift,periimplatitis

39
Q

Application al PRF in par ontology?

A

gingivalrecession,furcationdefects,regenerativeparodontological treatments

40
Q

After extraction impacted 3rd molar &
complicated healing? How PRF helps us?

A
41
Q

PRF in MRONJ:

A

medication -related osteonecrosis of jaw
can happen spontaneous or after intervention.

42
Q

PRF in MRONJ: 2

A

With the application more than 80% succesrate could be reach

Effects: formation of a fibrin network, adhesion of leukocytes and platelets, slow growth factor release, thereby increasing the regeneration tendency of soft and hard tissues

43
Q

PRF in cystectomy; after Removal cyst wall, we should do?

A

fill bone cavity with PRF

44
Q

what if we fill bone cavity by PRF
after cystectomy

A

y
- Formation fibrin mesh (then) stabilize blood
clot (then) helps bone regeneration.

45
Q

PRF in cystotomy (tos)

A

improve QOL
faster Regeneration

46
Q

PRF in Endodontics involve:

A
  • Apexifi cation
  • Direct pulp capping
47
Q

Direct pulp raping vs PRF?

A

PRF enhance: immun Response
increase dentin oogenesis
mineralization by slow release al growth
factor

48
Q

Best result of Direct pulp capping is use
of PRF and … together.

A

Mta

49
Q

MTA in Direct pulp capping increase…?

A

odontoblast differentiation

50
Q

pulp capping success depends on?

A

technique
material
tissue reaction

51
Q

Apexifi cation definition?

A

closing Apical foramen with medication.
usually calcium. hydroxide stakes 6 month.

52
Q

How result angiogenesis? (in Apexifi cation)

A

MTA + PRF + VEGF

53
Q

Apexification:
medication like (?)
after 6 month and several visit we see (?)

A

calcium-hydroxide
Apical barrier

54
Q

Apexification
medication like MTA
after How many visit we can see Apical plug

A

(2 visit)
(Apical plug) (not barrier)