Autogenous Blood Implant Flashcards
PRF vs PRP?
Second generate platlet concentrate
has higher release of Growth_hormone
Anticoag nadare
(Note) PRP All about platelet and Gf
By anticoag an centrifuge
20 years ago (planet) and (GF)
PDGF as key regulators during (?)
so aim was concentrate on these cells (using)
(?) and (?) so we call this phenomenon (?)/
wound healing
Anticoagulant
centrifuge device.
PRF
ADV of plat let concentrates.
- Autogenous tissue (Gold standard)
- Revascalarisation of tissue (Angiogenesis increase
- Recruiting various cell including stem cell
- proliferation (increase)
stage of wound healing?
I-P-R
informatory phase
proliferative phase
regenerative phase
informatory phase cells are contain:
Cytokines + (?) + blood coagulation + (?)
- Planets
- Growth factor
Informatory phase happen (?) after injury-
24-48 h
proliferative phase happen (?) after injury
3 days
proliferative phase cell’s is (?)
fibroblast
process of (?) happen in proliferative phase
- Angiogenesis
process of (?) happen in Regenerative.
- tissue regeneration
Regenerative phase cells?
- Newly organized Collagen fiber.
Role of planet in wound healing?
- key role in WH
-growth, Angiogenic factors, releasing
cytokine - low density
Role of white blood cell in WH?
- key role in WH
-growth, Angiogenic factors, releasing
cytokine - low density
Role of white blood cell in WH?
- Host defence
- Regenerative phase of healing
- Leukocyte
- high density
- Some to the RBCs
- hard to separate
What is PRP?
- high accumulation of plat let and growth
factor after centrifugation
How reach to prp?
- 30-60 minute centrifugation
- Use of anticoagulants together
Dis. ADV of PRP.
- long production time
- Use of anticoagulant (stop blood clotting
before application) - Liquid consistence.
(Exam) during PRP and centrifuge why do we
use of anticoagulant?
- to stop blood clotting before application
PRF First ADT?
- Less centrifuge time
- No anticoagulant adding
- Get consistence
- longer GF release profile
PRF composition? (not officially)
- No only GF and platlet But also (scafold)
- leukocyte between the Fibrin clot and red
corpuscles layer.
what is scaffold?
Scaffolds, typically made of polymeric biomaterials, provide the structural support for cell attachment and subsequent tissue development.
PRF composition (officially)
- Bioactive molecule (PDGF, TGF. B, VEGF, EGÉ
/ - provisional extracellular matrix/3D scaffold): Fibrin matrix •.
Fibronectin, vitro nectin
cell Type: Leukocyte_red blood cell
