Autoantibodies and Associated Disorders Flashcards

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1
Q

Anti-ACh receptor?

A

Myasthenia gravis

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2
Q

Anti-Basement membrane

A

Goodpasture syndrome

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3
Q

Anti-cardiolipin, lupus anticoagulant (2)

A

SLE, antiphospholipid syndrome

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4
Q

Anti-centromere

A

Limited scleroderma (CREST)

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5
Q

Anti-desmoglein

A

Pemphigus vulgaris

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6
Q

Anti-dsDNA, anti-Smith

A

SLE

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7
Q

Anti-glutamate decarboxylase

A

Type 1 DM

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8
Q

Anti-hemidesmosome

A

Bullous pemphigoid

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9
Q

Anti-histone

A

Drug-induced lupus

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10
Q

Anti-Jo-1, anti-SRP, anti-Mi-2 (2)

A

Polymyositis, dermatomyositis

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11
Q

Anti-microsomal, anti-thyroglobulin

A

Hashimoto’s thyroiditis

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12
Q

Anti-mitochondrial

A

Primary biliary cirrhosis

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13
Q

Anti-Nuclear

A

SLE, nonspecific

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14
Q

Anti-Scl-70 (anti-DNA Topo-I)

A

Diffuse Scleroderma

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15
Q

Anti-smooth muscle

A

Autoimmune hepatitis

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16
Q

Anti-SSA, Anti-SSB (anti-Ro, anti-La)

A

Sjogren

17
Q

Anti-TSH receptor

A

Graves

18
Q

Anti-U1 RNP (ribonucleoprotein)

A

Mixed connective tissue disease

19
Q

c-ANCA (PR3-ANCA)

A

Granulomatosis with polyangiitis (Wegener’s)

20
Q

IgA anti-endomysial, IgA anti-tissue transglutaminase

A

Celiac disease

21
Q

p-ANCA (MPO-ANCA) (2)

A

Microscopic polyangiitis, Churg-Strauss syndrome

22
Q

Rheumatoid factor (Anti-IgG-Fc IgM), anti-CCP

A

Rheumatoid arthritis