Autoantibodies

Question 1

What disorders are Antinuclear Ab’s (ANA) assoc w/?

Answer 1

SLE

nonspecific

Question 2

What disorder are Anti-dsDNA & anti-smith auto-Ab’s assoc w/?

Answer 2

SLE

Question 3

What disorder is Antihistone assoc w/?

Answer 3

Drug-induced lupus

Question 4

What disorder are Rheumatoid factor & anti-CCP assoc w/?

Answer 4

Rheumatoid arthritis

Question 5

What disorder is Anticentromere assoc w/?

Answer 5

Scleroderma (CREST synd)

Question 6

What disorder is Anti-Scl-70 (anti-DNA topoisomerase I) assoc w/?

Answer 6

Slceroderma (diffuse)

Question 7

What disorder is Antimitochondrial auto-Ab assoc w/?

Answer 7

Primary biliary cirrhosis

Question 8

What disorder are IgA antiendomysial & IgA anti-tissue transglutaminase assoc w/?

Answer 8

Celiac dz

Question 9

What disorder is Anti-basement memebrane assoc w/?

Answer 9

Goodpasture’s synd

Question 10

What disorder is Anti-desmoglein assoc w/?

Answer 10

Pephigus vulgaris

Question 11

What disorder are Antimicrosomial & Antithyroglobulin assoc w/?

Answer 11

Hashimoto’s thyroiditis

Question 12

What are Anti-Jo-1, anti-SRP & anti-Mi-2 assoc w/?

Answer 12

Polymyolitis & dermatomyositis

Question 13

What disorder is Anti-SSA (anti-Ro) assoc w/?

Answer 13

Sjögren’s synd

Question 14

What is Anti-SSB (anti-La) assoc w/?

Answer 14

Sjögren’s synd

Question 15

What disorder is Anti-U1 RNP (ribonucleoprotein) assoc w/?

Answer 15

Mixed CT dz

Question 16

What disorder is Anti-smooth muscle assoc w/?

Answer 16

Autoimmune hepatitis

Question 17

What disorder is Anti-glutamate decarboxylase assoc w/?

Answer 17

Type I DM

Question 18

What disorder is c-ANCA (PR3-ANCA) assoc w/?

Answer 18

Granulomatosis w/ polyangiitis (Wegner’s)

Question 19

What disorder is p-ANCA (MPO-ANCA) assoc w/?

Answer 19

Microscopic polyangiitis & Churg-Strauss synd