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Immunology > Autoantibodies > Flashcards

Autoantibodies Flashcards

1
Q

What disorders are Antinuclear Ab’s (ANA) assoc w/?

A

SLE

nonspecific

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2
Q

What disorder are Anti-dsDNA & anti-smith auto-Ab’s assoc w/?

A

SLE

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3
Q

What disorder is Antihistone assoc w/?

A

Drug-induced lupus

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4
Q

What disorder are Rheumatoid factor & anti-CCP assoc w/?

A

Rheumatoid arthritis

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5
Q

What disorder is Anticentromere assoc w/?

A

Scleroderma (CREST synd)

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6
Q

What disorder is Anti-Scl-70 (anti-DNA topoisomerase I) assoc w/?

A

Slceroderma (diffuse)

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7
Q

What disorder is Antimitochondrial auto-Ab assoc w/?

A

Primary biliary cirrhosis

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8
Q

What disorder are IgA antiendomysial & IgA anti-tissue transglutaminase assoc w/?

A

Celiac dz

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9
Q

What disorder is Anti-basement memebrane assoc w/?

A

Goodpasture’s synd

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10
Q

What disorder is Anti-desmoglein assoc w/?

A

Pephigus vulgaris

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11
Q

What disorder are Antimicrosomial & Antithyroglobulin assoc w/?

A

Hashimoto’s thyroiditis

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12
Q

What are Anti-Jo-1, anti-SRP & anti-Mi-2 assoc w/?

A

Polymyolitis & dermatomyositis

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13
Q

What disorder is Anti-SSA (anti-Ro) assoc w/?

A

Sjögren’s synd

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14
Q

What is Anti-SSB (anti-La) assoc w/?

A

Sjögren’s synd

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15
Q

What disorder is Anti-U1 RNP (ribonucleoprotein) assoc w/?

A

Mixed CT dz

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16
Q

What disorder is Anti-smooth muscle assoc w/?

A

Autoimmune hepatitis

17
Q

What disorder is Anti-glutamate decarboxylase assoc w/?

A

Type I DM

18
Q

What disorder is c-ANCA (PR3-ANCA) assoc w/?

A

Granulomatosis w/ polyangiitis (Wegner’s)

19
Q

What disorder is p-ANCA (MPO-ANCA) assoc w/?

A

Microscopic polyangiitis & Churg-Strauss synd

Immunology (7 decks)

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