Autoantibodies

Question 1

Myasthenia gravis is associated with what autoantibodies

Answer 1

Anti-ACh receptor

Question 2

Goodpasture syndrome is associated with what autoantibodies

Answer 2

Anti-glomerular basement membrane

Question 3

Antiphospholipid syndrome is associated with what autoantibodies

Answer 3

Anti-beta2 glycoprotein

Question 4

SLE, antiphospholipid syndrome is associated with what autoantibodies

Answer 4

Anticardiolipin, lupus anticoagulant

Question 5

Limited scleroderma (CREST syndrome) is associated with what autoantibodies

Answer 5

Anticentromere

Question 6

Pemphigus vulgaris is associated with what autoantibodies

Answer 6

Anti-desmoglein (anti-desmosome)

Question 7

Type 1 diabetes mellitus is associated with what autoantibodies

Answer 7

Anti-glutamic acid decarboxylase, islet cell cytoplasmic antibodies

Question 8

Bullous pemphigoid is associated with what autoantibodies

Answer 8

Anti-hemidesmosome

Question 9

Polymyositis, dermatomyositis is associated with what autoantibodies

Answer 9

Antisynthetase (anti-Jo-1), anti-SRP, anti-helicase (anti-Mi-2)

Question 10

Hashimoto thyroiditis is associated with what autoantibodies

Answer 10

Antimicrosomal, antithyroglobulin, anti-thyroid peroxidase

Question 11

Primary biliary cirrhosis is associated with what autoantibodies

Answer 11

Antimitochondrial

Question 12

Pernicious anemia is associated with what autoantibodies

Answer 12

Antiparietal cell, anti-intrinsic factor

Question 13

Primary membranous nephropathy is associated with what autoantibodies

Answer 13

Antiphospholipase A2 receptor

Question 14

Scleroderma (diffuse) is associated with what autoantibodies

Answer 14

Anti-Scl-70 (anti-DNA topoisomerase I)

Question 15

Autoimmune hepatitis type I is associated with what autoantibodies

Answer 15

Anti-smooth muscle

Question 16

Sjogren syndrome is associated with what autoantibodies

Answer 16

Anti-SS, anti-SSB (anti-Ro, anti-La)

Question 17

Graves disease is associated with what autoantibodies

Answer 17

Anti-TSH receptor

Question 18

Lambert-Eaton myasthenic syndrome is associated with what autoantibodies

Answer 18

Anti-presynaptic voltage-gated calcium channel

Question 19

Celiac disease is associated with what autoantibodies

Answer 19

IgA anti-endomysial, IgA anti-tissue transglutaminase

Question 20

Microscopic polyangiitis, eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome), ulcerative colitis are associated with what autoantibodies

Answer 20

MPO-ANCA/p-ANCA

Question 21

Granulomatosis with polyangiitis (Wegener) is associated with what autoantibodies

Answer 21

PR3-ANCA/c-ANCA

Question 22

Rheumatoid arthiritis is associated with what autoantibodies

Answer 22

Rheumatoid factor (IgM antibody against IgG Fc region0, anti-CCP (more specific)

Question 23

Nonspecific screening antibody, often associated with SLE is associated with what autoantibodies

Answer 23

Antinuclear (ANA)

Question 24

SLE is associated with what autoantibodies

Answer 24

Anti-dsDNA, anti-Smith, anti-histone

Question 25

Drug induced lupus is associated with what autoantibodies

Answer 25

Anti-dsDNA, anti-Smith, anti-histone

Question 26

Mixed connective tissue disease is associated with what autoantibodies

Answer 26

Anti-UI RNP (ribonucleoprotein)