Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharm2011 > Autacoids > Flashcards

Autacoids Flashcards

1
Q

What are autocoids?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are the 4 main classifications of autacoids?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the main function of autocoids?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Where was serotonin discovered?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What the functi9ons of seratonin in the CNS vs periphery?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

How is serotonin biosynthesis and degraded?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Where is serotonin mainly produced?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the role of platelets in working with seratonin?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

How many serotonin receptor subtypes are there?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Which serotonin receptor mediates platelet aggregation?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

How is 5-HT3 receptor related to vomiting?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

How do chemo drugs reduce vomiting?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Which serotonin receptor is involved in peristalsis?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Where are EC cells?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

When does peristalsis occur?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is IPAN?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What are the 2 types of GI motility?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What receptor subtype would you target for IBS?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What % of the population has IBS?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What antidepressant drug class is used to treat IBS?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Which 5-HT receptors are present in the CNS?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What does serotonin regulate in the CNS?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What are SSRIs used for?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Discuss the discovery of Histamine?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

How is histamine synthesised and metabolised?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

How is histamine distributed and stored?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

What are the two ways of histamine release?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

How many histamine receptor subtypes have been identified?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

How does mast cell degranulation occur?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

What is the triple response of lewis?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

How does histamine trigger a respone?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

What are the most common symptoms of allergic reactions?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

What is the mechanism of action of antihistamine?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

What are 5 clinical uses of H1 antihistamines?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

Discuss the discovery of NO.

A
36
Q

What is NO?

A
37
Q

How is NO biosynthesised?

A
38
Q

What are the isoenzymes of NOS (nitric oxide synthase)?

A
39
Q

Draw a diagram showing how NO induces blood vessel dilation.

A
40
Q

What 2 drug classes have bee developed to target NO production/ action?

A
41
Q

How does iNOS impact inflammation?

A
42
Q

What is nNOS and what does it do?

A
43
Q

What does nNOS do in the enteric nervous system?

A
44
Q

What does NO do in peristalsis?

A
45
Q

What is peptic ulcer disease (PUD)?

A
46
Q

What are the major functions of the stomach?

A
47
Q

How is gastric acid secreted and how does it stimulate the digestion of food?

A
48
Q

What are 3 endogenous stimulants of gastric acid?

A
49
Q

How is acid secretion inhibited?

A
50
Q

What are the 3 protective layers in the stomach’s mucosal defence?

A
51
Q

What are some causes of PUD?

A
52
Q

What is H. pylori?

A
53
Q

Discuss the discovery of H. pylori.

A
54
Q

Discuss the prevalence of H. pylori.

A
55
Q

Where does H. pylori live in the stomach?

A
56
Q

How does H- pylori protect itself from gastric acid?

A
57
Q

How does H. pylori cause stomach problems?

A
58
Q

What are the signs and symptoms of PUD?

A
59
Q

How is H. pylori spread?

A
60
Q

How is PUD treated?

A
61
Q

How can stomach pH be increased?

A
62
Q

Why are muscarinic antagonists not recommended to treat PUD?

A
63
Q

How do H2-receptor antagonists work?

A
64
Q

What is Nizatidine?

A
65
Q

What are Antacids?

A
66
Q

What makes Esomeprazole a useful PPI?

A
67
Q

When would IV PPI be indicated rather than oral?

A
68
Q

What is the mechanism of PPIs?

A
69
Q

What treatment is used to eradicate H. Pylori infections?

A
70
Q

What do amoxicillin antibiotics do?

A
71
Q

What do clarithromycin antibiotics do?

A
72
Q

What do esomeprazole or omeprazole antibiotics do?

A
73
Q

What is a migrane?

A
74
Q

What are the 3 types of migranes? What is their prevalence?

A
75
Q

What a severe risk factor of women with migranes?

A
76
Q

How is serotonin involved in migraines?

A
77
Q

What are 2 serotonin receptors involved in migraines?

A
78
Q

Draw a diagram showing how peripheral 5-HT can lead to pain and Aura in the CNS.

A
79
Q

What are 3 kinds of 5-HT related drugs that target migraines?

A
80
Q

What are Triptans?

A
81
Q

What is the clinical use of 5-HT1 agonists?

A
82
Q

What is the clinical use of 5-HT2 antagonists?

A
83
Q

What is the clinical use of 5-HT3 antagonists?

A
84
Q

What is the clinical use of 5-HT4 agonists?

A
85
Q

What is the clinical use of SSRIs?

A

Pharm2011 (7 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions