Auditory Flashcards

What do I absolutely need to know: 1. the auditory pathway 2. Rx: conduction disorders and tests 3. Sound Transduction/ regulation 1. Hair Cells (Organ of Corti) in: out: 2. bipolar cells (cochlear ganglion) in: out: 3. Cochlear Nerve (CN VIII) in: out: 4. Cochlear Nuclei in: out: 5. Cerebellopontine Angle (brainstem) in: out: 6. superior olivary nucleus 1. directly 2. through Trapezoid body 7. lateral lemniscus 8. Inferior Colliculus 9. Gyri of Heschl (temporal lobe

1
Q

inner hair cells

A

depolarize in response to sound conducted along the basilar membrane

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2
Q

outer hair cells

A

the electromotility of these cells modifies the sensitivity of the basilar membrane (cochlear amplification)

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3
Q

Rinne Test: conduction loss

A

the good ear lasts longer because it has air

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4
Q

Rinne Test: partial neural loss

A

both ears last roughly the same time

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5
Q

Weber Test: conduction loss

vibration is louder in the _____

A

affected ear

This is thought to occur because ambient sound is prevented from getting to the cochlea on the blocked side. This causes the nervous system to amplify sounds on that side by sensitizing cochlear transduction.

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6
Q

Weber Test: partial neural loss

vibration is louder in the ______

A

unaffected ear

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7
Q

Range of human hearing (low-high)

A

20-20,000 Hz

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8
Q

weber’s test: where is the fork placed?

A

vertex (middle) of head

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9
Q

rinne test: where is the fork placed

A

mastoid process

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10
Q

BAEPS:brain stem auditory evoked potentials

A

EEG detects neural response to click sounds to assess neural hearing loss

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11
Q

somatotrophy of basilar membrane of cochlea:

low vibrations are at the _____ of the cohclea

A

apex (end) of cochlea

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12
Q

tract: decussation occurs at

A

the trapezoid body

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13
Q

menier’s disease (endolympathic hydrops)

A

excess fluid in the inner ear- swellng of endolymphatic sac of idiopathic origin

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14
Q

acoustic neuroma

A

benign tumor of Schwann cells compresses CNVIII

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15
Q

tinnitus

A

auditory perception in the abscence of stimulus

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16
Q

ototoxic drugs

A

streptomycin or gentamicin

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17
Q

prebyacusis

A

loss of hearing with old age

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18
Q

hyperacusis

A

extra-sensitivity to moderate or even low intensity sounds

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19
Q

auditory agnosia

A

inability to identify meaning of an non-verbal sound; can hear, but don’t know what it means

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20
Q

congenital amusia

A

tone deafness, changes in pitch

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21
Q

timbre: brain region

A

right hemisphere/ cortex

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22
Q

music: rhythm/ pitch/ familiarity

A

left hemisphere

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23
Q

pitch (changes)

A

temporal regions of right hemisphere

24
Q

McGurk Effect

A

a mismatch between the sensation of sound and visual cue for a different letter result in perception of a third, unrelated sound.

25
angular gyrus
Important for matching graphemes to | phonemes (reading)
26
supramarginal gyrus
``` Important in matching incoming sounds to meaningful phonemes find individual neurons specific for different phonemes ```
27
arcuate fasciculus
White matter tract that connects Wernicke’s and Broca’s areas
28
conduction aphasia
lesion to arcuate fasciculus which connects broca's area to wernicke's area
29
Wernicke's Area
comprehension of speech
30
Wernicke's Aphasia
can produce speech but not comprehend it; word salad
31
Broca's Area
motor control of speech
32
phonemes
letters
33
lexemes
words/ sound groups
34
semantics
meaning of phonemes/ sound groups
35
syntax
rules of combinations of sound groups
36
dorsal stream
localization | superior parietal cortex, superior frontal gyrus
37
ventral stream
pitch primary auditory cortex inferior frontal gyrus
38
inferior colliculus
See integration of auditory information with inputs carrying somatosensory information from parts of the body Involved in the startle response to auditory stimuli and in the vestibulo-ocular reflex
39
MNTB: medial nucleus of trapezoid body
contains inhibitory neurons that decrease the activity of | lateral superior olive neurons)
40
cohclear amplifier
outer hair cells stiffen the basilar membrane and decrease its range of movement in relation to the tectorial membrane - this protects the cochlea from loud sounds
41
what is this process: the tensor tympani and stapedius muscles stiffen the ossicles in the middle ear to reduce transmission of loud, low frequency sounds to the inner ear
attenuation reflex
42
amplitude
loudness
43
frequency
ptich
44
complexity
timber
45
sound is heard longer through (air or bone)
air
46
sound is heard louder through (air or bone)
bone
47
timber
the sum of a variety of unequally weighted frequencies
48
somatotrophy of basilar membrane of cochlea: | high vibrations are at the _____ of the cohclea
base of cochlea
49
the endolymph is rich in _____
K+ | perilymph has low potassium
50
Tip Links
protein complexes that connect K+ channels at the tip of one stereocilia to the shaft of another sterocilia
51
K+ flows ____ during stereocilia depolarization
IN (due to the high concentration of K+ in the endolymph)
52
prestin
the motor protein responsible for expansion of outer hair cells during cochlear dampening
53
medial superior olive
localizes sound based on time delay
54
lateral superior olive
localizes sound based on intensity difference, regulated by MNTB
55
secondary "belt" areas
cells sensitive to specific combinations of sounds used in vocalization
56
Broca's Aphasia
can understand speech, but fail to produce it