AUBF Urinary System Flashcards
tube that connects urinary bladder to genitals
Urethra
functional unit of kidney that forms urine
nephrons
houses the glomerulus
Bowman’s capsule
Total renal plasma flow
600-700 mL/min
what part of kidney does not reabsorb water
Ascending loop of henle
Renin will react with _____ to produce Angiotensin I (inert).
Angiotensinogen
______ changes angiotensin I (inert) to angiotensin II (passive)
ACE (angiotensin converter enzyme)
Substance removed from the glomerular filtrate and returned to _______.
blood
Two ways or locations where reabsorption of substances happen.
- PCT and DCT to Peritubular capillaries
- LOH to vasa recta
substances reabsorbed through active transport
Glucose, amino acids, salts, chloride, sodium
Plasma concentration of a substance at which active transport stops & increased amounts are excreted in the urine.
Renal treshold
Final concentration of the filtrate through the reabsorption of water begins in the _____ and continues in the ______.
late distal CT; collecting ducts
Water reabsorption depends on the _____ in the medulla and the hormone ______.
osmotic gradient in the medulla and the hormone vasopressin.
secretion of sulfates, glucoronides, H+ and drugs happens in the
PCT
secretion of K+, ammonia and H+ happens in the
DCT and Collecting ducts
Passage (secretion) of substances from the peritubular capillaries to the renal tubules
Tubular secretion
The rate at which glomeruli in the kidney filter impurities in the blood.
Defined as the volume of plasma that can be completely cleared of a particular substance by the kidneys in a unit of time.
GFR or Glumerular Filtration Rate
Measure the rate at which the kidneys are able to remove a filterable substance from the blood; Standard test
Clearance Test
Factors in the selection of a clearance test substance:
Stability of a substance in urine during a 24-hour collection period
2. Consistency of the plasma level
3. Substances availability to the body
4. Availability of tests for analysis of the substance
Routine test for measurement of GFR
Crea Clearance
more sensitive than Creatinine Clearance; not reliable in patients w/ malignancy & immunologic disorders
Beta2 microglobulin clearance test
Small protein produced by all nucleated cells; Recommended for pediatric patients, diabetics, elderly,
and critically ill patients.
Cystatin C
Best test for quantitative measurement of renal concentrating ability
Osmometry
- make up 85% of the nephrons
- located in the cortex of the kidney
- For removal of wastes products and reabsorption of nutrients
Cortical nephrons
▪ longer Henle’s loops that extend in to the kidney medulla
▪ For concentration of urine
Juxtamedullary nephrons
small branch of the renal artery through which blood flows to the glomerulus of the kidney
Afferent Arteriole
coil of approx. 8 capillary lobes
Glomerulus
Forms the beginning of the renal tubule
Bowman’ capsule