Atrophic Vaginitis (Complete) Flashcards

1
Q

Define Atrophic Vaginitis

A

Inflammation and thinning of genital tissues due to reduced oestrogen levels, most commonly seen after menopause.

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2
Q

Atrophic Vaginitis is alternatively known as?

A

Vulvovaginal atrophy

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3
Q

What is the most common cause of atrophic vaginitis?

A

Menopause (Reduced oestrogen levels)

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4
Q

What are the main signs and symptoms of atrophic vaginitis

A

Sympmtoms:

Vaginal dryness and itching

Dyspareunia (Painful intercourse)

Vaginal discharge and inflammation

Urinary symptoms (Frequent UTIs)

Signs:

Thinning of vaginal mucosa (Loss of vaginal rugae)

Loss of pubic hair

Narrowed introitus (narrow vaginal opening)

Vaginal dryness

Spotting

Post-coital bleeding

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5
Q

Why is atrophic vaginitis associated with increased risk of UTI?

A

Changes in vaginal flora can result in increased bacterial infection due to proximity to urethra

Protective mucosal lining of the urinary tract is compromised in the absence of adequate estrogen

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6
Q

What differentials should be considered alongside atrophic vaginitis?

A

Red-flags:

Malignancy (Endometrial hyperplasia): Post-menopausal bleeding

STI: Vaginal itchiness/discharge

Female genital mutilation: Narrowed introitus

Other:

Vulvovaginal candidiasis

Lichen sclerosis

Lichen planus

Diabetes

UTI

Bladder dysfunction

Pelvic floor disfunction

Cystitis

Vaginismus

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7
Q

What differential should be considered if patient with atrophic vaginitis presents with post-coital bleeding or spotting?

A

Malignancy (Endometrial hyperplasia)

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8
Q

What differential should be considered if patient with atrophic vaginitis presents with dyspareunia?

A

Malignancy

Vaginismus

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9
Q

What differential should be considered if patient with atrophic vaginitis presents with urinary symptoms?

A

UTI

Pelvic floor dysfunction

Cystitis

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10
Q

What differential should be considered if patient with atrophic vaginitis presents has a narrowed introitus?

A

Female genital mutilation

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11
Q

What differentials should be considered if patient with atrophic vaginitis presents with vaginal dryness/itchiness?

A

STI

Vulvovaginal candidiasis

Skin conditions: lichen sclerosis, lichen planus, diabetes

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12
Q

What is lichen sclerosus?

A

Skin condition that causes itchy white patches on the genitals or other parts of the body.

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13
Q

What is lichen planus?

A

chronic inflammatory condition affecting the skin and mucosal surfaces

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14
Q

What examinations/investigations should be performed in patients suspected of atrophic vaginitis?

A

Bedside examinations::

Speculum examination (Vaginal signs of atrophy)

Bloods/Labs:

FBC: Check anaemia if any bleeding
Infection screen: If discharge and vaginal dryness

Imaging:

Transvaginal utrasound: Exclude endometrial cancer

Endometrial biopsy: Exlcude endometrial cancer

Biops of any abnormal skin lesions

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15
Q

What signs on speculum examination are suggestive of atrophic vaginitis?

A

Pale vaginal epithelium

Vaginal dryness

Loss of vaginal rugae

Thinning of vaginal epithelium

Erythema and inflammation

Petechiae (due to fragility of tissue)

Friability: Blood from speculum exaamination

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16
Q

What is the management plan for patients with atrophic vaginitis?

A

Non-hormonal treatment:

Lubricants: Short-term solution for vaginal dryness and dyspareunia

Moisturisers: Should be used regularly

Pharmacological treatment:

Topical oestrogen therapy: For local symptoms

Hormone replacement therapy (oral or transdermal): For systemic symptoms

Transvaginal laser therapy: Not currently reccomended

17
Q

What is transvaginal laser therapy?

A

Laser in the vagina to increase its strength and elasticity, to improve symptoms of urogenital atrophy

18
Q

How frequently should women using intravaginal oestrogen cream be reviewed?

A

Anually

N.B. Long-term effects of cream currently unknown