ATI Pharm Unit 1 Flashcards
transmission of medications from the locations of administrationto the bloodstream
absorption
refers to how medications travel through the body. they undergo a variety of biochemical processes that result in absrption, distribution, metabolism, and excretion.
pharmacokinetics
transportation of medications to sites of action by body fluids
distribution
___________ changes medications into less active or inactive forms byt the action of enzymes
(aka biotransformation)
metabolism
what is it called when some oral meds are inactivated on their first time through the liver, and therefore need a higher dose to achieve a therapeutic effect
first-pass effect
the elimination of meds from the body, primarily through the kidneys
excretion
term used for the safety margin of drugs
therapeutic index
the period of time needed for a medication to be reduced by 50% in the body.
half-life
interactions and effects that the drug has on the body and the cells
pharmacodynamics
type of medication that is stored in a skin patch and absorbed through the skin
transdermal
name of a medication determined by its chemical composition
chemical name
official or nonproprietary name given by the U.S. Adopted Names Council
generic name
proprietary name given by the company that manufactures the med
brand name (trade name)
what are the six “rights” of safe medication administration
right client right medication right dose right time right route right documentation
what are two major adverse effect risks for CNS meds
seizures
depression