Asystole Flashcards
1
Q
What is seen on ECG?
A
No QRS
P waves may persist
2
Q
How do you treat asystole?
A
Non-shockable
Adrenline 1 mg iv ASAP and every 3-5 minutes afterwards
3
Q
How does adrenaline stimulate relaxation?
A
Stimulates beta-1-arenoceptors Adenylyl cyclase (convert cAMP to ATP) cAMP increases protein kinase A - increase contractile protein sensitivity to calcium + phosphorylation of phospholamban Increase pumping of Ca into SR Increase rate of relaxation
4
Q
What is the effect of adrenaline on the heart?
A
Increase force, rate and cardiac output and O2 consumption
Decrease cardiac efficiency (O2 consumption > cardiac work)
5
Q
What are side effects of adrenaline?
A
Can cause arrythmias
6
Q
How is adrenaline administered?
A
IM/SC bolus
IV infusion
7
Q
Adrenaline has
(a) short
(b) long
half life?
A
Short
8
Q
Why and how is adrenaline given in acute cardiac arrest?
A
IV due to positive info/chronotropic actions (b1), redistribution of blood (a1) to the heart and dilation of coronary arteries (b2 on smooth muscle)
