Asthma & COPD Flashcards

1
Q

4 main sx of asthma?

A
  • SOB
  • wheezing
  • coughing
  • chest tightness
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2
Q

At what time of the day is asthma worse?

A

at night, early morning

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3
Q

What causes narrowing of airway tubes in asthma?

A
  • contraction of muscles in walls of airway tube
  • swelling of inner lining of airway tube
  • blockage of airway tube by mucous
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4
Q

Difference between asthma & COPD?
- cough
- FEV1
- triggers
- expiratory airflow

A
  • cough: nonproductive for asthma (worse at night & early morning), productive for COPD (throughout the day)
  • FEV1: reversible for asthma, irreversible for COPD
  • triggers: env triggers/infx/exercise for asthma, smoking / irritant exposure for COPD
  • expiratory airflow: variable for asthma, persistent for COPD
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5
Q

What is FEV1 and FVC?

A

FEV1 (forced expiratory vol in 1s): vol of air exhaled forcefully in the first second of maximal expiration

FVC (forced vital capacity): max vol of air exhaled after full inspiration

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6
Q

What is the FEV1/FVC for asthma & COPD? What is normal?

A

< 70% for both (obstructive disease)

Normal: 75-80%

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7
Q

How does the FEV1 and FVC improve in asthma after SABA?

A

FEV1 increases by ≥12%
FVC >200mL

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8
Q

What meds can possibly trigger asthma?

A
  • non selective BB
  • COX inhibitors (NSAID, aspirin)
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9
Q

Examples of SAMA?

A
  • ipratropium
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10
Q

Example of SABA?

A
  • salbuterol
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11
Q

Examples of LAMA?

A
  • tiotropium
  • umeclidinium
  • glycopyrronium
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12
Q

Examples of LABA?

A
  • formoterol
  • salmeterol
  • vilanterol
  • olodaterol
  • indacaterol
    (-terol)
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13
Q

Examples of ICS (asthma/COPD)?

A
  • budesonide
  • fluticasone
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14
Q

Minimum age to use turbuhaler? What strength is 1st line SMART?

A

12 years old
160/4.5 (b/f)

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15
Q

What are the two main characteristics of COPD?

A
  • chronic bronchitis: persistent cough + sputum production for most days of 3m in at least 2 consecutive years
  • emphysema: abnormal permanent enlargement of airspaces, destruction of walls
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16
Q

What are the 3 main sx of COPD?

A
  • SOB
  • chronic cough
  • sputum production
17
Q

At what age do pts usually present with COPD?

A

> 40y

18
Q

What is the FEV for the GOLD1, 2, 3 and 4 for COPD?

A

1: ≥80%
2: 50-79%
3: 30-49%
4: <30%

19
Q

For COPD, what is the risk of using ICS-LABA long term?

A

Increase risk of pneumonia

20
Q

Which antibiotics are used for COPD?

A

azithromycin

21
Q

What vaccinations should COPD patients receive?

A
  • influenza (annually)
  • pneumococcal (PCV13, PPSV23)
  • covid-19
  • Tdap
  • shingles