Asthma Flashcards
What is the forced expiratory volume?
The amount of air expelled when patient tries really hard
What are the 3 parts to ashma therapy?
Moniter lung function (forced expiratory volume)
Avoid triggers
Drugs to control symptoms
How does the SNS control bronchial tone?
NA & A in blood
β2 receptors = decreased mucous secretion into bronchial lumen & increase cAMP = bronchodilation
How does the PSNS control bronchial tone?
ACh
M3 receptors = increased mucous secretions into bronchial lumen & produce IP3 & Ca = bronchoconstriction
Is it the sympathetics or the parasympathetics that are activated in asthma?
Parasympathetics
In which 3 ways are asthma drugs administered?
Metered dose inhaler (liquid)
Spinhaler (powder)
Spacer dispenser
Which 3 drugs can induce asthma?
NSAIDs e.g. aspirin (increased leukotrienes)
Beta blockers e.g. propanolol & atenolol
Anticholinesterases e.g. neostigmine
Which 3 drug types do we use for long term control of asthma?
Beta 2 adrenoreceptor agonists
M3 muscarinic receptor antagonists
Phosphodiesterase inhibitor & adenosine antagonist (Theopylline)