Asthma Flashcards
What is asthma
chronic inflammation that leads to airway hyperresponsiveness
What are some common symptoms of Asthma patients?
Wheezing
Dyspnea
Chest tightness
Coughing
What is the Primary issue with asthma, as it relates to physiology?
Inflammation
Where is inflammation most pronounced
Medium-sized bronchi
Airway thickening is caused by what to airway smooth muscle?
Hypertrophy and hyperplasia of the airway smooth muscle
Airway hyper-responsiveness causes
Airway narrowing and remodeling
Subendothelial Fibrosis is caused by
deposition of collagen fibers underneath the basement membrane
What is the progressive Pathology of Asthma?
-Walls become inflamed and thicken
-air becomes trapped in alveoli
-Smooth muscles tighten
Predisposing factors of Asthma
Genetics
Race
Gender
Age (10-11 yrs)
Precipitating “triggers”
Environmental pollutants
Chemicals
Allergens
Exercise
Stress
How do you differentiate between symptoms of Asthma and COPD?
Asthma = usually asymptomatic between episodes
COPD = usually symptomatic
FEV1 is ______ in obstructive disorders
Reduced
FEV1/FVC is ______ in obstructive disorders
Reduced
FVC is _______ with obstructive disorders
Normal
What does a normal Spirometry Flow-Volume Loop look like?
Will descend in a straight or convex line