Asthma Flashcards
Definition of asthma
Heterogeneous disease characterized by chronic airway inflammation with history symptoms ( cough, breathlessness, wheezes, chest tightness ) and variable expiratory airway limitation
Which part of respiration is affected in asthma,
Inspiration or expiration
Expiration
What criteria allow for diagnosis of asthma
More than one type of these symptoms( wheeze, Shortness of breath, Cough, Chest tightness )
Symptoms worse at night or early morning
Vary over time and in intensity
Trigger of symptoms by viral infection, exercise , allergen, weather changes, laughter , irritants ( car fumes, smoke , strong smells
Symptoms that decrease diagnosis of asthma
isolated cough wiith no other respiratory symptom
Chronic production of sputum
Shortness of breath with dizziness , light headedness, peripheral tingling
Chest pain
Exercise induced Dyspnea wirh noisy inspiration stridor
Common trigger of asthma attack
viral infection URTI
Pollen
Animal dander
Dust
Smoke / fumes
Strong scent
Hoist dust mite , mold
Exercise
Strong emotions
Changes in temperature
Weather changes
Stress
Occupational exposure
Why asthma worsens at night
Because of cortisol level low at night which means that the body can’t fight inflammation as well as during the day when cortisol high
Factors that increase prevalence of asthma
parental history of asthma or atopy
Parental smoking - maternal smoking in pregnancy
Sensitization I to aeroallergens
Widespread use of antibiotic
Western lifestyle
Urban environnement
Diet
Factors that decrease prevalence of asthma
Farm environment
Older siblings
Viral infection
Earl attendance of day care during first 6 months of life
Tuberculosis
Symptoms pattern possible in asthma
Episodic or continuous
Seasonal or perennial
Nocturnal
Read pathophysiology of asthma
Okk
Findings of examination in asthma
Normal if no exacerbation
Lung hyperinflation
Wheezing
Allergic dx (rhinitis , sinusitis, nasal polyps , eczema)
Lung function test to demonstrated airflow limitation in asthma
Spirometry
Peak expiratory flow rate
Comorbidities in asthma
Sinusitis
Rhinosinusitis
COPD
GERD
OSA
How to diagnose asthma
Hx of symptoms
Examination
Lung function test (spirometry , PEF)
Comorbidities assessment
Broncho provocation test
Allergic states tests
FENO
FBC
CxR
Medications/activity used in bronchoprovocation test
Methcholine
Histamine challenge
Post exertion state