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Internal Medicine > Assignments Test 2 > Flashcards

Assignments Test 2 Flashcards

1
Q

In what stage of cancer is the cancer usually localized to the primary organ

A

Stage 1

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2
Q

A history of obesity or type 2 diabetes is a risk factor for which of the following cancers

A

All of the above

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3
Q

______ can be generated by translocation in which part kf one gene moves to a different chromosomes and recombines with another gene

A

Fusion proteins

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4
Q

Approximately what percent of clients with newly diagnosed cancers have clinically detectable metastasis

A

30%

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5
Q

What is the first level of dysplasia ?

A

Metaplasia

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6
Q

What type of malignant tumor originates from adipose tissue

A

Liposarcoma

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7
Q

Using TNM staging system what would be the grade I’d the cancer has no distant metastasis

A

M0

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8
Q

What gene appears to be the trigger of programmed cell death as a way of regulating uncontrolled cellular proliferation

A

P53

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9
Q

Which of the following organs is the most likely lovation of primary metastasis of bone cancer

A

Lungs

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10
Q

What are the most common of all metastatic tumors

A

Lung

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11
Q

What is the primary indication of theophylline

A

Bronchodilation

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12
Q

What is the drug class for albuterol

A

Bronchodilators

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13
Q

If a patient has a tumor in the pancreas what would it be the most common site of pain referral for this tumor ?

A

Shoulder,midthoracic,or low back

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14
Q

Cells are most sensitive to radiation therapy in the _____ phase

A

G2

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15
Q

What is the last step in the mitotic cycle before cell division

A

G2

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16
Q

Which chemotherapy agent bind to DNA and prevent DNA replication

A

Alkylating agents

17
Q

Tamoxifen in an antiestrogej hormonal agent is used in ______ to block estrogen receptors in the tumor cells that require estrogen to thrive

A

Breast cancer

18
Q

Monoclonal antibodies may be especially effective in treating certain cancers because these drugs

A

Bind to antigens on the surface of a particular type of cancer

19
Q

A relatively new strategy for treating certain tumors is to prevent the formation of new blood vessels, thus imparting tumor growth by starving the tumor of oxygen and nutrients. Drugs that use this strategy are known as

A

Angiogenesis inhibitors

20
Q

Most cancer chemotherapy agents exert severe and potentially toxic side effects because

A

Most of these drugs do not discriminate between healthy tissue and cancerous cell

21
Q

Some of the newer cancer chemotherapy agents are called biological therapies or biological response modifiers because they

A

Encourage the body’s immune system to fight cancerous cells

22
Q

The drug subclass of cytarabine is antimetabolites. What us the mechanism of action of cytarabine?

A

Inhibit DNA and RNA synthesis

23
Q

Which if the following healthcare professionals determines the delivery method and dosage of radiation therapy to be provided to a patient ?

A

Radiation oncologist

24
Q

Which of the following therapy options is considered as nonpharmacologicak modality for cancer pain

A

Relaxation training

25
Q

Which of the following concepts describe the theory that each round of chemotherapy will affect a certain percentage of cancerous cells and the chemotherapuetic regimen can never completely eliminate the tumor ?

A

Cell kill hypothesis

26
Q

Tumor lysis syndrome is a serious complications of chemotherapy that has significant adverse effects on the _________

A

Kidney

27
Q

A 37 yr old female has breast cancer. She is receiving FAC chemotherapy: Flouracil, doxorubicin, cyclophosphamide. What is the drug class of Fluorouracil?

A

Antimetabolites

28
Q

What is the trade name of doxorubicin ?

A

Adriamycin

29
Q

What is the drug class of cyclophosphamide ?

A

Alkylating agents

30
Q

What are the common adverse affects of cyclophosphamide (cytoxan)?

A

All of the above

31
Q

A 68 yr old pt presents with a history if chronic cough weight loss and hemostasis. Chest x ray reveals a mass in the right lung. A biopsy confirms the diagnosis of non small cell lung cancers.
Given the patients diagnosis which of the following imaging studies would be most appropriate to stade the tumor and assess for metastasis

A

Poitrob emission tomography

32
Q

The pt in the previous case received chemotherapy which includes a combination of agents such as doxorubin, bleomycin,vinblastine,and dacarbazine
To help the patient recover from chemotherapy induced Neutropenia, which if the following medications might the physician consider

A

Granulocyte colony stimulating factor
(G-CSF)

Internal Medicine (5 decks)

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