Assessment 1: Class 6 Flashcards

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1
Q

What are the phases of mitosis? (5)

A
  1. Prophase
  2. Prometaphase
  3. Metaphase
  4. Anaphase
  5. Telophase/Cytokinesis
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2
Q

How long does Prophase and Prometaphase last and what takes place?

A
  • About 36 minutes
  • Nuclear membrane breaks down
  • Centrioles duplicate
  • DNA condenses
  • Spindles begin to form
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3
Q

How long does Metaphase last and what takes place?

A
  • About 3 minutes
  • All the chromosomes line up at the ‘metaphase plate’ (not a physical structure, just the term for where they line up)
  • Microtubules from the spindle connect to the chromosomes
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4
Q

How long does Anaphase last and what takes place?

A
  • About 3 minutes
  • The glue that holds the sister chromatids together is broken down allowing them to separate
  • The chromosomes are pulled apart
  • Microtubules push the poles apart
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5
Q

How long does Telophase last and what takes place?

A
  • About 18 minutes
  • Since the cell is nearly done dividing, it begins to re-establish its normal structures as cytokinesis takes place
  • Mitotic spindle is broken down into its building blocks
  • Two nuclei form, one for each set of chromosomes
  • Chromosomes decondense and return to their stringy form
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6
Q

What is Cytokinesis?

A

The cytoplasmic division of a cell at the end of mitosis or meiosis, bringing about the separation into two daughter cells

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7
Q

What can go wrong? (2)

A
  1. Misregulation: Chromosome only gets 1 spindle fiber

2. Aneuploidy: The presence of an abnormal number of chromosomes e.g. 45 or 47 instead of the usual 46

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8
Q

What happens if a mutation occurs during G2?

A

There can only be 1 mutation because the DNA has already been duplicated

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