ASCO studies part 1 Flashcards
1
Q
all directly related to risk of recurrence in breast cancer.
A
Tumor size, involvement of axillary lymph nodes, and high nuclear and histologic grade are all directly related to risk of recurrence.
The number of involved axillary lymph nodes provides a semiquantitative assessment of risk of recurrence and death from breast cancer.
The expression of ER or PR by the tumor is a short-term favorable prognostic factor. Recurrent disease tends to develop more slowly during the first 4 to 5 years for patients with ER-positive or PR-positive tumors. Although several genomic-based assays provide independent prognostic information for both high and low risk patients, none of the individual markers listed (cathepsin D, bcl-2, and p53) are of known value.
