Artikelen + lecture week 4 Flashcards
What are the most commonly affected cognitive domains in MS?
The most commonly affected cognitive domains in MS are information processing and memory. Other cognitive symptoms include deficits in complex attention, executive functioning, verbal fluency, visuospatial perception, and social cognition.
What is the main problem with assessing cognitive function in MS in practice?
Cognitive function is not openly discussed, routinely assessed, or optimally treated despite being a common and highly disabling symptom of MS.
What is the Minimal Assessment of Cognitive Function in MS (MACFIMS) used for?
The MACFIMS is used to cover the essential components of a neuropsychological assessment to quantify MS-associated neurocognitive disorder.
Consists of multiple tests (o.a. PASAT & SDMT)
What is the Brief Repeatable Neuropsychological Battery (BRNB)?
The BRNB is a neuropsychological assessment that assesses the cognitive functions most likely to be impaired in MS.
It has the symbol digit modalities test (SDMT) & Paced Auditory Serial Addition test (PASAT)
What is the Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS)?
The BICAMS is a cognitive assessment that predicts actual performance of everyday tasks more accurately than self-report.
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What are the factors that impact cognition in MS patients?
Mood, fatigue, sleep problems, and medications can impact cognition in MS patients.
What factors can contribute to cognitive dysfunction in people with MS?
Depression, anxiety, sleep problems, medications, and cannabis use.
What is the recommended approach for comprehensive MS care?
Improved education, baseline screening, comprehensive cognitive assessment, and remedial interventions.
What is the most well-known cognitive screener for MS?
BICAMS (Brief International Cognitive Assessment for Multiple Sclerosis).
How does the lack of baseline assessment affect the detection of subtle changes in cognition in MS patients?
The lack of baseline assessment hampers the detection of subtle changes in cognition, especially when patients perform above norm scores.
What cognitive abilities are almost never impaired in MS?
Simple attention (repeating digits) and verbal abilities (naming, comprehension)
Also general intellect is intact and dementia is rare
The PASAT & SDMT are used for assessing which cognitive functions?
Information processing speed & attention
What is sensitivity?
Number of patients identified as cognitive impaired that are indeed suffering from the cognitive impairment
What is specificity?
Numer of patients identified as cognitive perserved that are indeed intact
