Arterial Hemodynamics Flashcards
What is pressure and what is it measured in?
The amount of force put on artery at any point in time.
Mm of mercury (mmHg)
How does the pressure change from the heart to the ankles?
Systolic increases
Diastolic decreases
Mean decreases (creates gradient)
What is kinetic energy and how much does it account for?
2 %
Energy created by the movement of blood
When does KE increase?
During exercise or within a stenosis
What is potential energy and how much does it account for?
98%
The main form of energy resulting from the pressure distending the vessels (stored within vessel walls).
What is flow?
The amount of fluid travelling past a point in a given amount of time
Units = volume/time (L/min)
What is the density of blood and does it change?
1.05 g/ml
No it is constant
What is viscosity?
The resistance of a fluid in motion to flow, the amount of frictional forces as the molecules move against one another. (Thickness of a fluid).
What is the most important factor affecting viscosity?
The concentration of RBC’s (hematocrit) and plasma protein.
How does length effect resistance?
A longer length of tube contains more resistance due to increased friction
How does radius effect resistance?
As radius decreases, resistance increases to the 4th power
What is resistance?
The force that must be overcome for flow to happen that is created by the friction of blood against the wall.
What is the most influential factor affecting resistance?
Radius
What does poiseuille’s law define?
The relationship between pressure, volume flow and resistance through a cylinder.
What is the equation for the Poiseille relationship?
Flow volume = (Pi x change in pressure) x r^4) divided by (8 x Length x viscosity)
What is the abbreviated formula of Poiseuille’s law?
Flow volume = Pressure gradient divided by the radius
What is the relationship between velocity and pressure?
Inverse
What is stroke volume?
The amount of blood ejected from the heart during systole
What dictates the stroke volume?
The arterial pressure and the peripheral resistance
What is systolic pressure?
Due to increased pressure from increased volume the artery walls expand creating PE within them.
What is the diastolic pressure?
As the volume and radius decreases during diastole, pressure decreases and blood flows due to its own momentum
What allows blood to flow?
The pressure gradient between the LV 120 mmHg and the RA (2-6mmHg)
What is hydrostatic pressure?
The force of gravity on a column of fluid