Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharm Block 6 > Arsenic poisoning > Flashcards

Arsenic poisoning Flashcards

1
Q

Which form is more toxic, trivalent or pentavalent?

A

trivalent

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are symptoms of acute toxicity?

A

intense GI distress, projectile vomiting, diarrhea, hypotension, RENAL TUBULAR NECROSIS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are symptoms of chronic arsenic toxicity

A

The THREE D’s: Dementia, dermatitis with altered pigmentation and keratoses, Diarrhea, polyneuritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

How does arsenic poisoning work - what’s the mechanism?

A

inhibits pyruvate dehydrogenase, blocks oxidative phosphorylation so causes acidosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Treatment for arsenic poisoning?

A

Dimercaprol (BAL) or succimer (chelators) + symptomatic support. Takes 1-3 weeks to recover. Use glucocorticoids for dermatitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are labs/findings for acute toxicity?

A

Hypotension, acidosis so increased respirations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what are labs/findings for chronic toxicity?

A

Glove and stocking distribution of burning sensation. Bilateral arm and leg weakness, Hyperpigmentation and thickening of skin on palms and soles, Aldrich-Mees lines on nails.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly

Pharm Block 6 (11 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions