argf Flashcards
- Which one of the following antiepileptic medications is considered a controlled
substance?
Phenobarbital (Luminal)
Which antidepressant is contraindicated in patients with a seizure disorder?
Bupropion (Wellbutrin)
Which of the following medications is NOT recommended for children under 12 years of
age?
Tramadol (ultram)
- Which of the following antidepressants is associated with the most weight gain?
Mirtazapine (Remeron)
- Acetaminophen is contraindicated in which of the following conditions?
Active hepatitis
Which of the following antiepileptic medications is known to cause a significant amount
of cognitive impairment and is associated with an increased risk of nephrolithiasis if th
patient is not adequately hydrated?
Topiramate (Topamax)
You give a patient hydrocodone/acetaminophen after care, what common side effect
should we warn zer about?
Constipation
- Endo patient who has history of NSAID induced GI bleeds, kidney disease and active
hepatitis, what is the best pain management regimen?
Oxycodone 5mg q6 hrs PRN x 3 days supply.
Which of the following medications is used for management of chronic neuropathic pain
and has been used for pre-operative and peri-operative analgesia in dental school and
other surgical procedures?
Pregabalin (Lyrica)
- Carbamazepine (Tegretol) and oxcarbazepine (Trileptal) are both antiepileptic
medications that can contribute to a condition known as syndrome of inappropriate
antidiuretic hormone (SIADH). One result from this condition is to develop a
hypervolemic _________
Hyponatremia
Which antidepressant is recommended as first line therapy in treatment guidelines for
depression?
Venlafaxine (Effexor)
- Mirtazapine (Remeron)
- Escitalopram (Lexapro)
- Which of the following antidepressants is associated with the most weight gain?
Zoloft
- Which of the following Rx is not recommended for kids less than 12 y.o.?
Tramadol- w/ acetaminophen is contraindicated for children younger than 12 due to
variability in metabolism.
- Requi9red on written prescription for oxycodone?
Dentist full name, address, signature, and patient full name and address ( A and C)
Seizure disorder type referred as “drop attack”, pt. wear helmet to protect their head?
Atonic
- Which antidepressant has been associated with bruxism?
Fluoxetine (Prozac)
Boi is treated for focal seizures with dysconitive features and 2 nd generalization with
carbamazepine. Boi is stabilized, no seizure after 2 weeks on carbamazepine, after 4
weeks, seizure frequency increases, durg level 5.6 mg/L. Wut the fak happened?
Metabolism autoinduction by carbamazepine.
Which of the following antiepileptic meds is known to cause sig. amounts of cognitive
impairment and associated with nephrolithiasis?
Topiramate (Topamax)
- Antidepressant’s MOA includes both serotonin and norepinephrine reuptake inhibitor?
Venlafaxine (efflexor)
- Recommended dose of acetaminophen by healthcare provider?
3mg, Elderly 2-3mg
- What type of a seizure is characterized by randomly falling and needing a helmet?
Atonic
- AD with most weight gain?
TCA- amitriptyline
Chronic and neuropathic pain?
TCA- amtryptiline
Venlafaxine (Effexor)?
Blocks the ne/5ht pump because it is an SNRI
Benzos can cause _______ with overdose?
CNS and respiratory depression
Akathisia is more common than other EPS
- Ariprazole-
increased prolactin (galactorrhea, gynecomastia etc)
Rispiridone:
Haloperidol:
highest risk for EPS
Sialorrhea
Clozapine:
Antidepressant with the least weight gain?
Bupropion
Drowsy, sedation, psychomotor impairment, blurred vision, ataxia, impaired memory,
risk for drug-to-drug interaction. No oral effects.
Question about main side effects of Benzos:
Which of the following adverse effects is specifically associated with the use of inhaled corticosteroids.
Oral candidiasis
GABA-A is coupled to what channels and is the mechanistic target for the therapeutic
benefits of benzodiazepines?
CHLORIDE
When prescribing an oral corticosteroid for its anti-inflammatory effects and pain
management to treat an inflammatory dental condition, what instructions should be
provided for administration?
Take in the morning with food.
The seizure medication that is most associated with a rash and requires a conservative
gradual dose titration when used with enzyme inhibitors or valproic acid?
Lamotrigine (Lamictal)
which of the following sets of lab orders ould be most appropriate when conduction
therapeutic drug monitoring for valproic acid?
Drug level, LFTs, platelets.
Which gland secretes mineralocorticoid and glucocorticoid hormone?
Adrenal gland
- Which side effect of Lexapro is NOT transient and does NOT subside with continued use?
Sexual dysfunction
therapeutic qualities of corticosteroids include?
Anti-inflammatory
- Which side effects occur most commonly with antidepressants?
Dysgeusia and xerostomia
A stress steroid cover dose of 10-25mg of hydrocortisone should be used for those with
Addison’s Disease who are at high risk of adrenal crisis in which of the following?
Major dental surgery
- What are the most common side effects associated with Remeron use?
Sedation and weight gain
Which antidepressant may be associated with an increased risk of bleeding and bruising
during and/or after a dental procedure?
Prozac
Which of the following are involved in the stimulation of the adrenal gland?
Hypothalamus and pituitary
Fludrocortisone is a/an:
Mineralocorticoid
Which antidepressant has been associated with bruxism?
Celexa
Which of the following adverse effects is associated with the use of corticosteroids?
Suppression of response to infection and insomnia
A dose reducing taper should be employed for a patient who receives prednisone for ____
days or more to avoid adrenal insufficiency?
14 days (2 weeks) or longer
- Proper disposal of short acting opioids includes all of the following options except:
Flushing down the toilet.
Which medication DOES NOT possess anelgesics and anti-inflammatory properties?
Acetaminophen
CP is a 59 y.o. undergoing endodontic treatment. MI one year ago?
Oxycodone
- Patients may experience increased CNS depression from benzodiazepines when suffering
from uncontrolled?
Hypothyroidism
Which antidepressants pharmacology involves increasing both NE and serotonin levels in
the brain?
All the above
Which of the following is indicated to treat hyperaldosteronism?
Spironolactone
Which MAO-I drug interaction can cause hypertensive crisis?
Tranylcypromine (Parnate) + pseudoephedrine (Sudafed)
Mineralocorticoids role in the body is to regulate:
Water and electrolyte balance
If a patient presents to the dental clinic with an oral infection that requires antibiotic
therapy, but possesses a sulfa allergy, you should avoid sulfa based antibiotics such as
sulfamethoxazole-trimethoprim Bactrim DS. If a patient for epilepsy, which of the following anti
epileptics should also be avoided in a patient with a sulfa allergy?
Zonsamide Zonegran
Liver func2on and platelet test
Valproic acid?
Oxycarbamazipine?
SIADH
Divalproic acid?
Thrombocytopenia
Carbmazapine?
D and Ca supplement
Keppra?
Renal func2on test
Prozac?
Decrease platelet aggrega2on.
Celexa?
Bruxism
increase NE and sero
all
Hypothyroidism?
Increase in opioid seda2on effects
Hyperthyroid increase
epidemic effects
Hyperaldosteronism?
Spironolactone
Mirtazipine:
highest risk of dry mouth (compared to SSRI and SNRI)
Sexual dysfunc2on:
not transient
TCA’s (nortryl2line, amtryp2line) casue
increase seda2on from opiods
Naloxone can be given
every 2-3 minutes
Need to taper cor2costeroid a_er
14 days
Pregabalin?
Seizure med can also be used for neuropathic pain or pe:
celicoxib
Selec2ve Cox 2 inhibitor