1 Flashcards
If a patient presents to the dental clinic with an oral infection that requires antibiotic
therapy, but possesses a “sulfa allergy”, you would avoid sulfa-based antibiotics such as
sulfamethoxazole-thrimethoprim (Bactrim-DS). If a patient is being treated for epilepsy,
which one of the following antiepileptics should also be avoided in a patient with a
“sulfa” allergy?
Zonisamide (Zonegran)
When administering carbamazepine (Tegretol) one must always consider the potential
for drug interactions. One of the most common pharmacokinetic interactions with
carbamazepine would result from its induction of which ONE of the following
cytochrome P450 enzymes?
a. 3A4
How long should duloxetine (Cymbalta) be continued after achieving remission in a
patine tfollowing their first episode of depressiong?
9-12 months
What herbal product is recommended in treatment guidelines for depression?
St. John’s wort
Which antidepressant’s mechanism of action includes both serotonin and NE reuptake
inhibition?
Venlafaxine (Effexor)
Which oral side effect occurs most commonly with antidepressants?
Xerostomia
Which side effect of citalopram (Celexa) is NOT transient and does NOT subside with
continued use?
Sexual dysfunction
A 23 yo male patient is presenting with complaints of tooth and gum. JB’s history is
positive for Focal Seizures with Dyscognitive Features and Major Depressive Disorder.
JB’s current medications include clonazepam (Klonopin) for anxiety, phenytoin (Dilantin)
for seizurews, gabapentin (Neurontin) for seizures, and sertraline (Zoloft) for
depression. Upon examination, JB is found to have a moderate case of gingival
hyperplasia. Which of the following medications is most likely to contribute to the
development of gingival hyperplasia?
Phenytoin
Before she leaves the office you should educate her/her caregive on which of
the following?
a. Do not drink alcohol while on this medication and do not take other medications
that cause drowsiness, unless under the supervision of a health care provider.
b. It is important to use this medication as directed. Do not drive or operate
machinery until you know how this medication will affect you.
c. This medication has abuse potential. You. Should ensure safe storage, including
keeping it out of reach of children and dispose of any unused tablets by placing
them in a nondescript container with coffee grounds or kitty litter.
d. All of the above
All
- Which treatment, initated 24 hours beore a dental procedure decreases postoperative
edema and improves healing time?
a. Ibuprofen (Motrin)
Which is a pure opioid antagonist that blocks opioid receptors and is used to reverse
opioid overdoses?
Naloxone (Narcan)
NSAIDs are contraindicated or should be used with cuation in patients with which
condition?
Chronic kidney disease
Many antidepressants including tricyclic antidepressants (TCAs), monoamine oxidase
inhibitors (MAOis), and selective serotonin reuptake inhibitors (SSRIs) have the potential
to lower the seizure threshold. Which one of the following antidepressants has specific
labeling that suggests a maximum daily dose of 400 to 450 mg in part because of the risk
of seizure activity beyond this?
Bupropion (Wellbutrin)
Ibuprofen is likely to cause a drug interaction with which of the following?
Warfarin (Coumadin)
- Which one of the following tests is most likely to assist in making an accurate diagnosis
of a seizure disorder?
EEG
- Calicum and vitamin D supplementation is recommended for patients taking which ONE
of the following antiepileptic medications?
Valproic acid (Depakote)
