3 Flashcards
Which antidepressant’s mechanism of action includes only serotonin reuptake inhibition?
a. Fluoxetine (Prozac)
b. Bupropion (Wellbutrin)
c. Venlafaxine (Effexor)
d. Mirtazapine (Remeron)
a. Fluoxetine (Prozac)
Which antidepressant has the lowest risk of weight gain and sexual dysfunction?
a. Fluoxetine (Prozac)
b. Bupropion (Wellbutrin)
c. Venlafaxine (Effexor)
d. Mirtazapine (Remeron)
B
What is the risk associated with using a monoamine oxidase inhibitor antidepressant with an over the counter cold preparation
containing pseudoephedrine?
A
What is the risk associated with using a monoamine oxidase inhibitor antidepressant with any of the following medications:
dextromethorphan, meperidine, tramadol, or methadone?
a. Serotonin syndrome
b. QT prolongation
c. Seizures
d. Hypertensive crisis
A
Which antidepressant has the highest risk of mortality associated with an overdose?
a. Sertraline (Zoloft)
b. Duloxetine (Cymbalta)
c. Mirtazapine (Remeron)
d. Amitriptyline (Elavil)
D
Which statement is true regarding the efficacy of antidepressants?
a. SSRI antidepressants are recommended first line based on superior efficacy
b. SNRI antidepressants are recommended first line based on superior efficacy
c. Current evidence suggests all antidepressants demonstrate similar efficacy
d. Remission rates are approximately 70% for all antidepressants
C
Which benzo has the shortest duration of action?
a. Alprazolam (Xanax)
b. Chlordiazepoxide (Librium)
c. Clonazepam (Klonopin)
d. Diazepam (Valium)
A
Which medication would have the fastest onset of efficacy for the treatment of acute anxiety?
a. Buspirone (Buspar)
b. Lorazepam (Ativan)
c. Sertraline (Zoloft)
d. Venlafaxine (Effexor)
B
What mechanism of action do risperidone and ziprasidone have in common for treating schizophrenia?
a. D2 agonist
b. D2 antagonist
c. D2 partial agonist
d. D2/5HTA2 antagonist
D
Which antipsychotic has the greatest risk of metabolic side effects such as weight gain, hyperglycemia, and hyperlipidemia?
a. Aripiprazole (Abilify)
b. Haloperidol (Haldol)
c. Olanzapine (Zyprexa)
d. Risperidone (Risperdal)
C
Which antipsychotic has the greatest risk of EPS disorders/tardive dyskinesia?
a. Quetiapine (Seroquel)
b. Clozapine
c. Haloperidol (Haldol)
d. Risperidone (Risperdal)
C
What is the proposed mechanism of action of haloperidol and chlorpromazine for treating schizophrenia?
a. D2 agonist
b. D2 antagonist
c. D2 partial agonist
d. D2/5HTA2 antagonist
A
Based on treatment guidelines, which antipsychotic would be considered first line therapy in a patient newly diagnosed with
schizophrenia?
a. Aripiprazole (Abilify)
b. Clozapine
c. Haloperidol
d. Chlorpromazine
A
What is the max recommended daily dose for acetaminophen?
a. < 3 grams/day for adults and 2-3 grams/day for children
a. < 3 grams/day for adults and 2-3 grams/day for elderly
b. < 5 gms/day for aults and <4 gm/day for elderly
c. < 13gm/day for adults and <12-13/day for elderly
d. < 15gm/day for adults nad <14 gm/day for elderly
A
What patient risk factors are important to asses when considering treating pain with NSAIDs?
a. History of GI problems and GI risk factors
b. Cardiovascular conditions and CV risk factors
c. Renal dysfunction
d. A&B
e. E. all of the above
E
TT is a 66 year old patient with post extraction pain. His primary care physician does not want him to take NSAIDs because the patient
is on warfarin. You have prescribed him 2 days of opioid therapy. TT should be educated to monitor for which common adverse
effect?
a. Diarrhea
b. Headache
c. Constipation
d. Insomnia
C
- What is the problem when you have a diet high on Tyramine?
a. Hypertensive Crisis
- If you take Prozac and you combine it with another drug that
has Seritonin what happens?
a. Seritonin Syndrome
- Which antidepressant has the highest risk of mortality
associated with an overdose?
- Which antidepressant has the highest risk of mortality
associated with an overdose?
a. Amitriptyline (TCA)
Which of the following medications is the first line of treatment
a. Answer Sertraline (SSRI)
What are the main side effects for a patient on an SSRI?
are the main side effects for a patient on an SSRI?
a. Nausea, vomiting, diarrhea
- What is the common drug for GAD (generalized Anxiety
disorder), SAD (social), panic disorder?
a. Answer is SSRI (Fluxetine, Prozac)
- Which drug has both Seritonin and NE reuptake inhibition?
a. Venlafaxine (Effexor) SNRI
b. Prozac (SSRI)
c. Celexa (SSRI)
d. Wellbutrin (NDRI)
A
What is a 5HT alpha 1 partial agonist?
a. a. buspar
The recommended length of time for someone that has
experience depression for the first time is?
a. 9-–12 Mo after remission
b. 5 years
A
The first symptom that is seen on someone who starts taking
an antidepressant is?
a. Decreased anxiety, improvement of sleep and
improvement of appetite
b. Energy levels
A
- What is the mechanism of action of Buspar?
a. 5HT1A partial agonist
Benzodizepines are given for a parson that is going through?
a. Alcohol withdrawal – if acute
b. Depression
c. Seizures
d. All of the above
C and A i think
- Which of the following is true about Benzodizepine?
a. Quick onset
b. Long half life
A
Which drug is associated with tardive dyskinesia?
a. Haloperidol (HALDOL)
All benzodiazepines have the potential for?
Quick onset
Not the potential for abuse
Short dosages
Long half life
Quick onset
Pathway involved with Proactolemia ?
a. a. Tuberoinfundibular
Which antipsychotic has the greatest risk of tardive
dyskinesia?
a. Haloperidol (Haldol)
Muscarinic M1 receptor is involved with?
a. Urinary retention, decreased cognition,
tachycardia, dry mouth, blurred vision,
constipation
- Patient presents with the symptoms of extreme motor
restlessness, inability to sit still?
a. Akathisia (we are confused between the answer
choice being TD or Akathisia)
- What causes Agrunolocytosis?
a. Clozapine
What is a treatment of choice for refactory
schizophrenia?
a. Clozapine
What drug causes excess of weight gain?
a. Olanzapine
These drugs have decrease incidences of EPS?
Lorazpan
Which ONE of the following antiepileptic medications should be discontinued if a rash develops?
a. Phenobarbital
b. Levetiracetam (Keppra)
c. Lamotrigine (Lamictal)
d. Topiramate (Topamax)
C
Which ONE of the following antiepileptic medications is associated with the development of gingival hyperplasia?
a. Phenytoin (Dilantin)
b. Iamotrigine (Lamictal)
c. Divalproex (Depakote)
d. Carbamazepine (Tegretol)
A
Which ONE of the following antiepileptic medications would be most likely to contribute to a potential drug interaction with oral
contraceptive medications resulting in a decreased level of effectiveness of the contraceptive?
a. Lamotrigine (Lamictal)
b. Carbamazepine (Tegretol)
c. Levetiracetam (Keppra)
d. Alprazolam (Xanax)
B
A medication that causes dry mouth, dry eyes, and constipation is likely to exhibit which one of the following receptor activities?
a. Dopamine blockade
b. Inhibition of serotonin reuptake
c. Alpha-1 receptor blockade
d. Anticholinergic/antimuscarinic
D
The antiepileptic that is most often associated with concerns about cognitive impairment and requires a gradual dosage titration in
part for this reason is which one of the following?
a. Topiramate (Topamax)
b. Zonisamide (Zonegran)
c. Divalproex (Depakote)
d. Oxcarbazepine (Trileptal)
A
What is the max recommended daily dose for acetaminophen?
a. < 3 grams/day for adults and 2-3 grams/day for elderly
b. < 5 gms/day for adults and < 4 gm/day for elderly
c. < 13 gm/day for adults and < 12-13 gm/day for elderly
d. < 15 gm/day for adults and < 14 gm/day for elderly
A
What patient risk factors are important to asses when considering treating pain with NSAIDs?
a. History of GI problems and GI risk factors
b. Cardiovascular conditions and CV risk factors
c. Renal dysfunction
d. all of the above
D