2 Flashcards

1
Q

What is the proposed mechanism of action of buspirone (Buspar) for treating anxiety?

a. 5-HT2A receptor antagonist
b. GABA-B receptor agonist
c. 5-HT1A receptor partial agonist
d. GABA-A receptor agonist

A

C

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2
Q

What medication is the treatment of choice for anxiety disorders including generalized
anxiety disorder, panic disorder and social anxiety disorder?
a. alprazolam (Xanax)
b. sertraline (Zoloft)
c. pregabalin (Lyrica)
d. buspirone (Buspar)

A

B

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3
Q

Which antipsychotic is associated with sialorrhea?
a. Risperidone (Risperdal)

b. Aripiprazole (Abilify)
c. Clozapine (Clozaril)
d. Lurasidone (Latuda

A

C

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4
Q

Which antipsychotic has the greatest risk of tardive dyskinesia?
a. Risperidone (Risperdal)
b. Clozapine (Clozaril)
c. Haloperidol (Haldol)
d. Quetiapine (Seroquel)

A

C

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5
Q

What is the proposed mechanism of action of aripiprazole (Abilify)for treating
schizophrenia?
a. D2/5HT2A antagonist
b. D2 antagonist
c. D2 partial agonist/5HT2A antagonist
d. D2 agonist

A

C

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6
Q

Mechanism of action for Aripiprazole?

A

Partial D2 agonist, 5HT2A antagonist

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7
Q

What would you prescribe a pt who just experienced their first schizophrenic episode?

A
  1. Apiprazole
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8
Q

Which drug is well suited for treating refractory schizophrenia?

A

Clozapine

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9
Q

What is the primary advantage of using a second generation antipsychotic over first
generation?

A

No risk of EPS

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10
Q

What receptor does Lorazepam act on?

A
  1. GABA-A
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11
Q

Quick onset benzos are more likely to be abused

A

Quick onset benzos are more likely to be abused

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12
Q

First line therapy for depression

A

SNRIs, SSRIs, mirtazipine, bupropion

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13
Q

Benzos:

A

GABA-A

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14
Q

First line therapy for depression

A

SNRIs, SSRIs, mirtazipine, bupropion

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15
Q

Benzos:

A

GABA-A

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16
Q

Benzo has

A

cns and resp dep in overdose

17
Q

Use benzos with caution

A

with opioids

18
Q

Aripiprazole- akathisia is more

A

Aripiprazole- akathisia is more common than other EPS

19
Q

Rispiridone:

A

inc prolactin (galactorrhea, gynecomastia etc)

20
Q

highest risk for EPS

A

Haloperidol:

21
Q

extreme motor restlessness/inability to sit still

A

Akathisia:

22
Q

Clozapine:

A

agranulocytosis

23
Q
  1. AD with least weight gain?
A

Bupropion