Arboviruses

Question 1

Arboviruses are ________-borne viruses: vectors are usually ______ and _____.

All contain RNA/DNA? and All are enveloped/ unenveloped?.

T or F humans are not dead end hosts?

Answer 1

Arthropod; Mosquitoes and ticks.

RNA; Enveloped

False; humans Are dead end hosts.

Question 2

Outcome of arbovirus depends of 3 things

Answer 2

1) specific viral agent
2) age of patient
3) Extent to which encephalitis develops.

Question 3

Diagnosis of Arbovirus:
____ antibody capture ELISA.

_____ sample is the easiest.

Answer 3

IgM antibody.
can also add virus-specific monoclonal antibodies to increase specificity.

CSF.

Question 4

Culture of arbovirus is NOT/ VERY typical?

Answer 4

Not

Question 5

How come NAT testing of Reverse transcriptase-based PCR of RNA genome of Arbovirus not reliable in acute phase?

Answer 5

Viremia is ofter weak and transient.

Question 6

To ensure further viral transmission of arbovirus the animal must have a titer higher than______.

Answer 6

10^4.

Question 7

1) Humans are tangetial hosts accidentally entering a natural zoonotic transmission cycle.
2) Large human population coexisting with large vector population such as mosquitoes?

Which one is Sylvatic cycle and which is Urban Cycle?

Answer 7

1) Sylvatic

2) Urban

Question 8

Encephalitis definition

Answer 8

S/S’s indicating involvement of brain parenchyma

Seizures, alteration of consciousness, visual disturbances, paralysis of extremities.