Arbo - WNV Flashcards

1
Q

Enzootic Vector

A

Culiseta meanura

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2
Q

Brdige vector

A

Coquiiettida perturbans

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3
Q

Main Epizootic Vector

A

Culex

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4
Q

WNV Types

A

Type II - Africa - Low Path
Type I - US - High Path

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5
Q

Enzootic Reservoir

A

Songbird

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6
Q

Susceptible birds

A

Corvids

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7
Q

Mortality in hosts

A

Bats, rabbits, chipmunks, squirrels, horses, alpaca, cats, dogs

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8
Q

Seropositive only

A

Dogs, bears, sheep, goats, wolfs

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9
Q

Subclinical ratio

A

1:9

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10
Q

Serious manifistations %

A

Ataxia - 86
Depression - 51
Hindlimb weakness - 49
Rising - 46
Tremors - 41
Fever only - 24
Death - 25 - 33

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11
Q

Neurological Lesions

A

Brain stem
-Spinal cord ataxia
-Hypersthesia
-Muscle fasiculations

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12
Q

Behavior changes

A

Nonresponsive
Somnolence
Seizures

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13
Q

Colorado Study

A

Recovery - 82%
Residual - 21%

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14
Q

Unreported rate

A

2/3

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15
Q

Florida study

A

Residual - 15%
Follow up - 6 months
Neurologic - 60%
Duration - 35 days

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16
Q

Residual Effects

A

Behavior
Loss of muscle mass
Stumbling
Low energy
Abnormal gait
Vision loss
Dysphagia
Relapse (2 weeks - 5 months)

17
Q

Diagnosis

A

Clinical signs
CSF - mononuclear pleocytosis, normal to increased
IgM antigen-capture ELISA
Plaque reduction neutralization assay
PCR, IHC

18
Q

Prevention

A

Killed virus vaccine
Canary pox vectored vaccine
Chimera virus - WNV & Yellow Fever