Approach to Poisonings Flashcards
What are the components of the coma cocktail?
- Oxygen
- POC glucose
- Naloxone
What are the four major questions to ask with an ingestion?
- What was ingested
- When
- How much
- Why
What are the 7 aspects physical exam that require particular attention to in the cases of an ingestion/poisoning?
- VS
- Mental status
- Pupils
- skin color
- Track marks
- diaphoresis
- Bladder size
What are the components of the DUMBBELS mnemonic for cholinergic poisoning?
Diarrhea Urination Miosis Bronchorrhea Bradycardia Emesis Lacrimation Salivation
What are the s/sx of ANTIcholinergic poisoning?
Mad as a hatter Blind as a bat Hot as hell Red as a beet Dry as a bone
What are the s/sx that differentiate between sympathomimetic poisoning vs anticholinergic?
Sympathomimetic will have diaphoresis
Anticholinergic will have reduced or absent BS
What is the drug that mimics opioid intoxication?
Clonidine
What causes the anion gap with ASA poisoning?
Uncoupling of oxidative phosphorylation
What causes the QRS prolongation with TCAs?
Na channel blockade
What causes the QTc prolongation with antipsychotics?
K channel blockade
Where is methanol usually found in?
Windshield wiper fluid
Where is ethylene glycol usually found?
Antifreeze
Why does ethylene glycol cause renal failure?
Oxalate is the metabolite, binds with Ca leading to stones.
