Applied Pharmacology Flashcards
What is the difference between DMARD’S and SMART drugs?
SMART drugs are used to relieve the symptoms - they do not alter the course of the disease.
DMARD’s are used to attempt to slow the progression of the disease itself, prevent further joint destruction and may induce a remission.
Biophosphonates are commonly prescribed drugs in the management of osteoporosis. How do they work?
By reducing the amount of osteoclast mediated bone resorption.
Which over-the-counter drug is contraindicated in a patient with acute gout?
Aspirin.
Explain the action of rubefacients. Why are they used?
These are drugs, which, when applied to skin, cause reddening of the skin by increasing blood flow. They initiate signals which compete with pre-existing pain impulses for access to the CNS. Blood vessels dilate and create sense of warmth.
Used for strains, sprains and other local lesions.
