apoptosis Flashcards

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1
Q

apoptosis

A

controlled death of cells within our body which plays an important role in our development

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2
Q

necrosis

A

death of cells through injury disease, whole areas of tissue are effected(infection)

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3
Q

stages in apoptosis

A
  1. cell begins apoptosis once separated from other cells
  2. collapse of cells cytoskeleton
  3. cell shrinkage
  4. breakdown of organelles and nucleus
  5. blebbing of plasma membrane
  6. budding of plasma membrane-bound vesicles called apoptotic bodies then phagocytosis
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4
Q

errors in apoptosis

A

to much apoptosis can result in neurodegenerative disease, as cells die that are not meant to die
to little apoptosis can result in
cancer and uncontrolled cell division and the subsequent development of a tumour.

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5
Q

mitochondrial (intrinsic) pathway

A

the pathway of apoptosis which
is initiated by the detection of internal cellular damage

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6
Q

death receptor (extrinsic) pathway

A

the pathway of apoptosis which is initiated by the reception of extracellular death signalling molecules

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