Aortic Stenosis Flashcards
what is the most common cause of AS?
degenerative
what does degeneration do to the valve
calcifies it
degeneration is an inflammatory response involving ________and________-. The lesions contain ______ which calcify
is an inflammatory response involving macrophaes and t lymphocytes. The lesions contain lipoproteins which calcify
what is a more common cause of AS in the young?
congenital e.g. bicuspid valve
what are some other causes of AS?
- rheumatic - This is not seen frequently anymore.
rheumatic HD tends to affect the _____ valve
mitral
what does rheumatic fever do to the valve
results in fusion, thickening and calcification of the valve
valvular aortic stenosis should be distinguished from other causes of obstruction to left ventricular emptying which include:
- supravalvular obstruction
- hypertrophic cardiomyopathy
- subvalvular aortic stenosis
Obstructed left ventricular emptying leads to increased ___ ______r pressure and compensatory ___ _____
hyper- trophy. In turn, this results in relative _____ of the left ventricular myocardium, and consequent angina, ______ and _______ ventricular failure .
Obstructed left ventricular emptying leads to increased left ventricular pressure and compensatory left ventricular hyper- trophy. In turn, this results in relative ischaemia of the left ventricular myocardium, and consequent angina, arrhyth- mias and left ventricular failure.
what are the symptoms? SAD
- syncope/dizziness
- angina
- dyspnoea
why do you get ischaemia?
because of LV hypertrophy- the heart has to work harder to get blood through the narrowed valve
_____ is an emergency in AS
syncope
what are the characteristics of the pulse in AS?
Low volume pulse - slow rising and weak
why is the pulse low volume ?
this is because AS means you can’t get blood from the main pump of the heart to the body
what is the apex beat like in AS?
Forceful displaced apex - due to LV hypertrophy