Ao arch anomalies Flashcards
Embryology aortic arch system
- Aortic arches: paired arteries from aortic sac on ventral surface of embryo
o Paired dorsal aorta - Total of 6 paired Ao arches develop, not present at same time
- Surround esophagus and trachea
- Modified during development to form major component of arterial system
o All of mature Ao arch structures lie on L side of esophagus/trachea
Except birds: normally have R Ao arch
Which arch regress
1,2,5
3rd arch becomes
internal common carotids
L 4rth arch become
portion of Ao root, join persistent L dorsal Ao
R 4rth arch become
R subclavian artery
6th arch become
R: RPA
L: LPA + DA
Dorsal Ao become
L: desceding Ao
R: portion of R subclavian
7th intersegmental arteries become
L subclavian
Which species do 5th Ao arch do not regress
Reptiles
Species differences in BCT
- Eq, Bo: 1 BCT
- Ca, Fe, Po, rabbits/mice: BCT + L subclavian
- Hu, Rat: BCT + L subclavian + R common carotid
most common vascular anomaly
PRAA
Breeds PRAA
o ↑ incidence: German Shepherd, Irish Setter
o Also reported in Geart Dane
Pathophys PRAA
o Absence of L aortic arch → R Ao arch persists
o Ring formed w/ L sided DA + PA → entrapment of esophagus btw PA, trachea and ligamentum/PDA
DDX PRAA
o Double Ao arch
o Retroesophageal L or R subclavian artery
o R ligamentum arteriosum
C/s PRAA
typically swallowing difficulties
o Young animal
o Regurgitation after meal
o Thin/emaciated animal with normal heart/lungs
CTX changes PRAA
- Radiographs: air, fluid filled esophagus cranial to heart
o Dilation starts at thoracic inlet
o End abruptly at heart base
o On DV: mediastinal dilation cranial to heart with S shaped trachea on right