Anxiety Flashcards
what acts as the emotional filter of the brain for assessing whether sensory material via the thalamus requires a stress or fear response
amygdala
acute stress leads to dose-dependent increase in what
catecholamines and cortisol
_____ acts to mediate and shut down the stress response
cortisol
through negative feedback, cortisol acts on what
pituitary
hypothalamus
hippocampus
amygdala
acute stress _____ cortisol levels
increases
what is an automatic though
thought that pops into your head throughout the day
what is a schema
a deep rooted unconditional belief that stems from childhood experience. they shape assumptions and automatic thoughts
what is GAD
anxiety that is not restricted to, or strongly predominating in any particular environment - free floating
what makes anxiety qualify as GAD
long lasting (most days for 6 months) not controllable causing significant distress/impairment in function
what is the typical age of onset of GAD
20-40
what is the course of GAD
chronic and fluctuating
is GAD more common in women or men
women
__% are co-morbid with other psychiatric disorders
90
what is the first line treatment of GAD
CBT
what pharmacological methods can be used to treat GAD
SSRI - sertraline
SNRI - venlafaxine
pregabalin
Benzodiazepines (ST only)
what investigations would be done for GAD
ECG
PFTs
TFTs
FBC
when do problems with benzos arise
if used over 2 weeks
what kind of problems arise with benzos
sedation and psychomotor impairment
withdrawal problems
can worsen depression
nausea and headache
how do you treat an overdose of benzodiazepines
flumazenil
what kind of withdrawal symptoms are seen with benzos
rebound anxiety
insomnia
irritability
delirium
how do benzos work
enhance the effect of GABA –> sedation, muscle relaxation, anticonvulsant effects, reduced anxiety
GABA channels allow __ influx
Cl-
what is panic disorder
recurrent attacks of severe anxiety which are not restricted to any particular situation or set of circumstances and so attacks are unpredictable
what are s/s of panic disorder
sudden onset of palpitations, chest pain, choking sensation, dizziness, unreality