Anxiety

Question 1

GAD(Generalised anxiety disorder): Drugs

Answer 1

1st – SSRIs: escitalopram, paroxetine, sertraline
Venlafaxine
BDZs: diazepam, alprazolam
Imipramine 
Buspirone
Hydroxyzine

Question 2

Adverse Effects: GAD drugs

Answer 2

Confusion, dizziness, drowsiness
Dry mouth, fatigue, headache
Dizzy, N, muscarinic

Question 3

Mechanism of action: GAD Drugs

Answer 3

Inhibit na and 5HT reuptake
Partial 5HT1A agonists
Selective H1 receptor inverse agonist

Question 4

Interactions: GAD Drugs

Answer 4

NSAIDs, antipsychotics
AEDs, some opioids
Opioids, AEDs

Question 5

Drugs used for panic disorder

Answer 5

1st – All SSRIs
TCAs: clomipramine, imipramine
BDZs: alprazolam, diazepam, lorazepam
Venlafaxine
Reboxetine

Question 6

Drugs used for social phobia

Answer 6

1st – SSRIs: excitalopram, fluoxetine, paroxetine, sertraline, fluvoxamine           
BDZs: bromazepam, clonazepam            
Venlafaxine
Moclobemide             
Gabapentin + pregabalin            
Olanzapine

Question 7

Drugs for Simple phobia

Answer 7

1st – psychological

Consider paroxetine or BDZs

Question 8

PTSD

Answer 8

SSRIs: fluoxetine, paroxetine, sertraline
TCAs: amitriptyline, imipramine
Mirtazapine
Venlafaxine
Lamotrigine

Question 9

OCD
Drugs 
Adverse effects 
Mechanism of action
Interactions

Answer 9

SSRIs - Clomipramine
N+V+D, dizzy, dry mouth, drowsy, fatigue
Inhibit NA and 5HT
Beta blockers, NSAIDs