Antiviral SE and Resistance Flashcards

1
Q

Ribavirin:

A

Hemolytic Anemia

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2
Q

Acyclovir

A

SE: Obstructive Crystalline nephropathy, ARF

Resistance: mutated viral thymidine kinase

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3
Q

Ganciclovir

A

SE: pancytopenia, Renal TOxic

Resistance: Mutated CMV DNA polymerase, lack of viral kinase

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4
Q

Foscarnet

A

SE: Nephrotoxic

Resistance: Mutated DNA polymerase

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5
Q

Cidofovir

A

SE: Nephrotoxic (used w/ probenecid and IV saline)

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