Antiviral SE and Resistance Flashcards
1
Q
Ribavirin:
A
Hemolytic Anemia
2
Q
Acyclovir
A
SE: Obstructive Crystalline nephropathy, ARF
Resistance: mutated viral thymidine kinase
3
Q
Ganciclovir
A
SE: pancytopenia, Renal TOxic
Resistance: Mutated CMV DNA polymerase, lack of viral kinase
4
Q
Foscarnet
A
SE: Nephrotoxic
Resistance: Mutated DNA polymerase
5
Q
Cidofovir
A
SE: Nephrotoxic (used w/ probenecid and IV saline)