Antiviral Agents Flashcards
What are the viruses that respond to antiviral therapy?
Influenza A, herpes virus, cytomegalovirus, HIV, AIDS, some respiratory viruses, and some viruses that cause warts and eye infections
What are the characteristics of antiviral drugs?
- Able to enter the cells infected with the virus
- Interfere with viral nucleic acid synthesis and/or regulation
- Interfere with the ability of virus to bind to cells
- Stimulate the body’s immune system
What are the common respiratory viruses?
Influenza A, influenza B, and RSV in children
Signs and symptoms of respiratory viruses
Cough, fever, inflammation of the nasal mucosa, and inflammation of the mucosa of the respiratory tract
How do influenza A and respiratory virus drugs work?
By preventing shedding of the viral protein coat
What are the pharmacokinetics of Influenza A and respiratory virus drugs?
Administer orally and excreted unchanged in the urine
When would you not give a patient Influenza A and respiratory virus drugs?
When the patient has an allergy, is pregnant, or is lactating
Dizziness, insomnia, nausea, and orthostatic hypotension are adverse reactions of what type of drugs?
Influenza A and respiratory virus drugs
What drugs will cause a drug-drug interaction with influenza a and respiratory virus drugs?
Anticholinergic agents
What are the common anti-viral agents?
- Amantadine (symmetrel
- Oseltamivir (Tamiflu)
- Rimatadine (Flumadine)
What is the prototype of respiratory antiviral agents
Rimatadine
How do respiratory antiviral agents work?
By inhibiting viral replications, possibly by preventing the uncoating of the virus
