Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology Final Exam > Antiviral Agents > Flashcards

Antiviral Agents Flashcards

1
Q

What is the suffix for agents for herpes and cytomegalovirus?

A

“-Clovir”
-Acyclovir
-Ganciclovir
-Valacyclovir
-Valganiclovir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

How do you remember the drug names for Nonnucleoside reverse transcriptase inhibitors (NNRT’s)?

A

“-vir-“
-Delavirdine
-Efavirenz
-Nevirapine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

How do you remember the names for Nucleoside reverse transcriptase inhibitors (NRTI’s)?

A

“ZALE T”
-Zidovudine
-Abacavir
-Lamivudine
-Emtricitabin
-Tenofovir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the suffix for protease inhibitors?

A

“-Navir”
-Daranavir
-Fosamprenavir
-Lopinavir
-Ritonavir
-Tipranavir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the suffix for integrase strand transfer inhibitors?

A

“-gravir”
-Dolutegravir
-Raltegravir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Agents for influenza A and respiratory viruses

A

Tadine or mivir
-Amantadine used for influenza A and West Nile virus. can be used for some movement dz including ms
-Oseltamivir decreased duration and severity if taken shortly after symptoms begin
-Peramivir (intravenous)
-Rimantadine
-Zanamivir (inhaled)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Anti-hepatitis B agents

A

-Adefovir
-Entecavir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the name of the fusion inhibitor and what does it do?

A

Enfuvirtide- Drug that stops HIV from binding to the cell membranes, which decreases the spread of infection.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the CCR5 coreceptor antagonist and what does it do?

A

Maraviroc
A type of drug that blocks the receptor site that HIV binds to in healthy cells which prevents the spread of the infection.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Anti hepatitis C agents

A

Velpatasvir; sofasbuvir; ledipasvir- Sofosbuvir; glecaprevir-pibrentasvir; elbasvir-grazoprevir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Locally active antiviral agents

A

Docosanol; ganciclovir; penciclovir, acyclovir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

True or false: both hep B and C can be cured

A

False. Only hepatitis C can be cured

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is AIDS related complex (ARC)?

A

Refers to a group of symptoms that occur in individuals who are hiv positive but don’t meet the criteria for an aids diagnosis.
Helper T cell count hasn’t reached the cuff for it to be considered aids.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is Acquired immunodeficiency syndrome (AIDS)?

A

Condition is caused by HIV. # of T-cells decreased to a certain point then the decreased immunity allows for opportunistic infections and cancers.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is cytomegalovirus (CMV)?

A

A DNA virus that can infect people of all ages. Often remaining dormant in the body after initial infection. Mostly affects the lungs, eyes, and the liver.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is a helper T-cell and what does it do?

A

A lymphocyte that helps kick off the immune system

17
Q

Which is most sever? Hepatitis B or C?

A

Hepatitis B is more severe. It is a virus that affects the liver and can be fatal. It is transferred through the blood.

18
Q

Hepatitis C

A

A virus that like hep B, attacks the liver but is less severe. Although pts may need a liver transplant over some time

19
Q

What is the DNA virus that causes chicken pox or varicella zoster and causes geneital herpes, cold sores and can cause encephalitis?

A

Herpes

20
Q

What is an interferon?

A

Hormone that tissues release when there is viral replication going on- it stops further replication with non nucleoside reverse transcriptase inhibitors. They are released in response to the presence of a viral infection. “Interfere” with the replication of pathogens.

21
Q

What is the common cold or common flu?

A

Influenza A- spread through respiratory droplets.

22
Q

What is the corona virus?

A

A group of RNA viruses that mostly cause respiratory problems. - COVID-19 is a type of the corona virus

23
Q

Integrase Strand transfer inhibitor

A

“-gravir”
Drug that blocks integrase, which is a vital part of replication

24
Q

NonNucleoside reverse transcriptase inhibitors

A

“-vir-“
Drugs that bind to the reverse transcriptase, which is essentially responsible for breaking down cell DNA. Stops viral DNA replication and stops viral replication.

25
Q

Nucleoside revers transcriptase inhibitors

A

“ZALE T”
Bind to the reverse transcriptase that is responsible for inserting viral DNA, which also stops replication.

26
Q

Protease inhibitors

A

“-Navir”
Inhibit the protease enzyme in HIV
This prevents immature HIV cells from becoming fully mature infective HIV cells.

27
Q

What is a virus?

A

Tiny bit of DNA or RNA that is protected by a protein coat. Lives by hijacking other cells to do its bidding.

28
Q

How are does calculated in children for antivirals?

A

Doses should be calculated by weight

29
Q

Why should extreme caution be used when giving anti virals to children?

A

There are no proven safety measures for use in children

30
Q

What should be closely monitored if using antivirals in children?

A

Kidneys, bone marrow, liver

31
Q

What is important for you to inform adults about antivirals?

A

They cannot be used for bacterial infections.
If used incorrectly they could cause drug resistance for both viral and bacterial infections.
Antivirals cannot cure HIV dz they can only slow HIV from progressing.

32
Q

Why should patients take precautions in getting sick such as keeping up with vaccines?

A

Because someone with HIV has a weak immune system which allows for opportunistic illnesses to be contracted more easily.

33
Q

True or false: Pregnant women can take antivirals

A

False. Severe fetal effects
-HIV can be passed through milk

34
Q

When would doses of antivirals need to be lowered for older adults?

A

If they have renal or liver dysfunction because they may be worsened by these medications. They are also more susceptible to adverse effects

35
Q

What labs should be monitored regularly in a patients with HIV and AIDS?

A

Renal and hepatic - before and periodically during therapy

Pharmacology Final Exam (11 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions