Antiviral Flashcards

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1
Q

NRTI + rash

A

Abacavir

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2
Q

NRTI + pancreatitis

A

Didanosine

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3
Q

NRTI + oral ulcers

A

Zalcitabine

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4
Q

NRTI + bone marrow suppression

A

Zidovudine

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5
Q

NNRTI Examples

A

NEED

Nevirapine
Efavirenz
Efravirine
Delavirdine

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6
Q

NNRTI + rash

A

Nevirapine

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7
Q

Effective in preventing vertical transmission of HIV during labor

A

Nevirapine

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8
Q

NNRTI + weird dreams

A

Efavirenz

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9
Q

Protease inhibitor examples and common side effect

A

-navir

Inhibits carbohydrate and lipid metabolism
All are substrates and inhibitors of CYP3A4 (esp ritonavir)

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10
Q

Binds to gp41

For persistent HIV 1 replication

A

Enfuvirtide

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11
Q

Binds to ccr5

A

Maraviroc

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12
Q

Inhibits integrase

For treatment-naive HIV

A

Raltegravir

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13
Q

Nucleoside reverse transcriptase inhibitors (NRTI) examples

A

-vudin plus ZAD

Zalcitabine
Abacavir
Didanosine

All cause lactic acidosis

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