Antiviral Flashcards
NRTI + rash
Abacavir
NRTI + pancreatitis
Didanosine
NRTI + oral ulcers
Zalcitabine
NRTI + bone marrow suppression
Zidovudine
NNRTI Examples
NEED
Nevirapine
Efavirenz
Efravirine
Delavirdine
NNRTI + rash
Nevirapine
Effective in preventing vertical transmission of HIV during labor
Nevirapine
NNRTI + weird dreams
Efavirenz
Protease inhibitor examples and common side effect
-navir
Inhibits carbohydrate and lipid metabolism
All are substrates and inhibitors of CYP3A4 (esp ritonavir)
Binds to gp41
For persistent HIV 1 replication
Enfuvirtide
Binds to ccr5
Maraviroc
Inhibits integrase
For treatment-naive HIV
Raltegravir
Nucleoside reverse transcriptase inhibitors (NRTI) examples
-vudin plus ZAD
Zalcitabine
Abacavir
Didanosine
All cause lactic acidosis